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The Laboratory Mouse 3rd Edition by Mark A Suckow, Sara Hashway, Kathleen R Pritchett Corning ISBN 0367373203 9780367373207

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The Laboratory Mouse 3rd Edition Mark A. Suckow Digital Instant Download

Author(s): Mark A. Suckow, Sara Hashway, Kathleen R. Pritchett-Corning
ISBN(s): 9780367373207, 0367373203
Edition: 3rd
File Details: PDF, 19.04 MB
Year: 2023
Language: english
SKU: EB-47734804 Category: Tags: , ,

The Laboratory Mouse 3rd Edition by Mark A Suckow, Sara Hashway, Kathleen R Pritchett Corning – Ebook PDF Instant Download/Delivery: 0367373203, 9780367373207
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ISBN 10: 0367373203 
ISBN 13: 9780367373207
Author: Mark A Suckow, Sara Hashway, Kathleen R Pritchett Corning

With the advent of transgenic and other genetic engineering technologies, the versatility and usefulness of the mouse as a model in biomedical research has soared. Revised to reflect advances since the second edition, The Laboratory Mouse continues to be the most accessible reference on the biology and care of the mouse in research settings. This guide presents basic information and common procedures in detail to provide a quick reference source for investigators, technicians, and caretakers on the humane care and use of the mouse. The new edition adds information on novel technologies such as CRISPR-Cas and on housing systems and management practices; it covers new concepts such as pain assessment by facial expression and the importance of nest-building as an assessment tool of well-being. There are now expanded sections on anesthesia and analgesia, and on behavior and enrichment. An ideal quick reference for investigators, technicians, and animal caretakers charged with the care and/or use of mice in a research setting, this book will be particularly valuable to those new to working with mice who need to start research programs using these animals.

The Laboratory Mouse 3rd Table of contents:

1 important biological features
introduction
stocks and strains
nomenclature
anatomic and physiologic features
normative values
Basic Biologic Parameters
Clinical Chemistry
Urinalysis
hematology
immunodeficient mice
wild mice
behavior, well-being, and enrichment
Behavior
Well-being
Enrichment
references
2 husbandry
housing
Caging
Housing Systems
Bedding
barriers and containment
personal protective equipment (PPE)
special considerations for immunodeficient mice
environment
Temperature and Humidity
Ventilation
Illumination
Noise and Vibration
sanitation and pest control
Sanitation
Cage cleaning
Room cleaning
Research equipment cleaning
Quality control
Pest Control
nutrition
water
breeding
Basic Genetics
Breeding Schemes
Pheromone Influences
Timed Pregnancy
Genetic Monitoring
identification and record keeping
Identification
Records
transportation
Between Institutions
Within the Institution
references
3 management
regulatory agencies and compliance
Institutional Animal Care and Use Committee (IACUC)
IACUC Composition
Responsibilities of the IACUC
occupational health and zoonotic diseases
compassion fatigue
references
4 clinical medicine
basic veterinary supplies
physical examination of the mouse
common spontaneous and noninfectious diseases
Common Conditions Involving the Alimentary System
Non-neoplastic conditions
Alimentary tumors
Common Conditions Involving the Cardiovascular System
Non-neoplastic conditions
Cardiovascular tumors
Common Conditions Involving the Endocrine System
Non-neoplastic conditions
Endocrine tumors
Hematopoietic and Immune System
Non-neoplastic conditions
Hematopoietic and immune system tumors
Common Conditions Involving the Integumentary System
Non-neoplastic conditions
Tumors of skin and adnexae
Common Conditions Involving the Musculoskeletal System
Non-neoplastic conditions
Musculoskeletal tumors
Common Conditions Involving the Nervous System
Non-neoplastic conditions
Nervous system tumors
Common Conditions Involving the Respiratory System
Non-neoplastic conditions
Respiratory tumors
Common Conditions Involving the Urogenital System
Non-neoplastic conditions
Urogenital tumors
Common Systemic or Multisystem Conditions
Amyloidosis
Hyalinosis
Conditions related to nutritional status
Stress-related changes
common infectious diseases
Diagnostic Methods
Viral Agents and Diseases
Murine noroviruses (MNV)
Parvoviruses
Mouse hepatitis virus (MHV)
Theiler’s mouse encephalomyelitis virus (TMEV)
Mouse rotavirus (MRV, EDIM)
Murine astrovirus
Mouse adenoviruses (MAV 1 and 2)
Lymphocytic choriomeningitis virus (LCMV)
Lactate dehydrogenase–elevating virus (LDV, LDEV)
Hantaviruses (Han)
Herpesviruses
Ectromelia virus (mousepox)
Papovaviruses
Paramyxoviruses
Reovirus 3 (REO3)
Bacterial Agents and Diseases
Bordetella species
Filobacterium rodentium (formerly cilia-associated respiratory bacillus, CAR bacillus, CARB)
Citrobacter rodentium
Clostridium piliforme
Corynebacterium bovis
Helicobacter
Mycoplasma
Rodentibacter pneumotropicus and R. heylii (formerly Pasteurella pneumotropica type Jawetz or Heyl)
Pseudomonas aeruginosa
Staphylococcus
Fungal Agents and Diseases
Pneumocystis murina
Intestinal protozoa
Parasitic Agents and Diseases
Arthropods
Helminths
treatment and supportive care of sick mice
Drug Dosages
General Treatment of Open Skin Lesions
General Treatment of Weak Mice
Provision of supplemental fluids
Provision of food
Provision of supplemental heat
Treatment of Dystocia
clinical endpoints
treating disease on a colony basis
Prevention of Spread
Approaches to Elimination
Depopulation
Test and cull
Burnout
Medical treatment
Facility Decontamination
references
5 preventive medicine
receiving
Reviewing Health Reports
Options for Newly Imported Mice
Transport directly to barrier
Quarantine
Rederivation
Cryopreservation
testing of biological materials
Risks for Humans and Animals
health surveillance and monitoring
Principles
Selection of Test Subjects
Diagnostic Testing
disease prevention through sanitation
references
6 experimental methodology
restraint
Cage Transfer
Restraint for Manipulation
Restraint Devices
sampling methods
Blood
Urine
Feces
Samples for DNA Analysis
Vaginal Swabs
compound administration
Oral (PO)
Intramuscular (IM)
Intraperitoneal (IP)
Subcutaneous (SC)
Intradermal (ID)
Intravenous (IV)
Retro-orbital (RO)
Implantable Cannulas and Pumps
anesthesia and analgesia
Anesthesia
Methods and drugs
Periprocedural Care
Analgesia
euthanasia
Laws, Regulations, and Guidelines
Management Considerations
Scientific Considerations
Experimental Endpoints
Euthanasia Methods
necropsy
Equipment and Materials
Necropsy Procedure
External examination
Dissection and specimen collection
Trimming tissues for histology
Histopathology
Reporting and archiving data and specimens
references
7 resources and additional information
organizations
American Association for Laboratory Animal Science (AALAS), www.aalas.org
Laboratory Animal Management Association (LAMA), www.lama-online.org
American Society of Laboratory Animal Practitioners (ASLAP), www.aslap.org
American College of Laboratory Animal Medicine (ACLAM), www.aclam.org
Laboratory Animal Welfare Training Exchange (LAWTE), www.lawte.org
Institute for Laboratory Animal Research (ILAR), www.nationalacademies.org/ilar/institute-for-laboratory-animal-research
AAALAC International, www.aaalac.org
Foundation for Biomedical Research (FBR), fbresearch.org
National Association for Biomedical Research (NABR), www.nabr.org
publications
Books
Guideline Documents
Periodicals
electronic resources
appendix
suggested cassette numbering system and some trimming suggestions

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