The Eicosanoids 1st Edition by Peter Curtis Prior 9780471489849 0471489840

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Product details:

ISBN 10:0471489840 
ISBN 13:9780471489849
Author:Peter Curtis Prior

This comprehensive reference work, updated from the first edition, brings together the knowledge and expertise of contributors from around the world. It includes new topics such as prostaglandin synthetase enzyme, new synthetic eicosanoids, innovative analytical methods, the influence of cytokines in the regulation of synthesis and actions, newer eicosanoids that influence the cardiovascular system, and newly discovered roles in reproduction and interactions with nitric oxide.

This book satisfies a surge of interest in prostaglandins―NSAIDS (e.g. aspirin) are the biggest selling drugs of all time, and the field has been refreshed by the advent of new types (selective COX-2 inhibitors, anti-leukotiene drugs).

The Eicosanoids 1st  Table of contents:

CHAPTER 1
Perspectives on the Biosynthesis and Metabolism of Eicosanoids 

CHAPTER 2
Control of Eicosanoid Production by Cellular and Secreted Phospholipase A2

CHAPTER 3
Mechanisms of PGH Synthase-1 (COX-1) Activity and Role of Radical States 

CHAPTER 4
Regulation and Function of Prostaglandin Synthase 2/Cyclooxygenase II 

CHAPTER 5
Mammalian Lipoxygenases

CHAPTER 6
Biosynthesis and Biological Effects of 5-oxo-ETE and Other Oxoeicosatetraenoic Acids

CHAPTER 7
Synthetic Eicosanoids

CHAPTER 8
Perspectives of Analytical Methods for Eicosanoids

CHAPTER 9
Enzyme Immunoassays of Metabolites and Enzymes Using Acetylcholinesterase as Label 

CHAPTER 10
Bioassay of Eicosanoids 

CHAPTER 11
Gas Chromatography and Mass Spectrometry in Eicosanoid Analysis

CHAPTER 12
Time-Resolved Fluoroimmunoassay in Eicosanoid Analysis 

CHAPTER 13
Perspectives and Clinical Significance of the Biochemical and Molecular Pharmacology of Eicosanoids

CHAPTER 14
Eicosanoid Antagonists

CHAPTER 15
Biosynthesis and Degradation of Anandamide, An Endogenous Ligand of Cannabinoid Receptors 

CHAPTER 16
Inhibitors of Eicosanoids 

CHAPTER 17
Biology and Chemistry of Products of the Isoprostane Pathway

 

CHAPTER 18
Insight into Prostanoid Functions: Lessons from Receptor-Knockout Mice

 

CHAPTER 19
Perspectives and Clinical Significance of Eicosanoids in Immunology, Endocrinology and Metabolic Regulation

 

CHAPTER 20
Prostaglandins and the Immune Response

 

CHAPTER 21
Leukotrienes in Aspirin-Intolerant Asthma

 

CHAPTER 22
Essential Fatty Acids 

 

CHAPTER 23
Endothelial Secretory Function and Atherothrombosis

 

CHAPTER 24
Molecular Regulation of Pancreatic Islet Prostaglandin Synthesis and Its Relevance to Diabetes Mellitus

 

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