The Delta Receptor 1st Edition by Kwen Jen Chang, Frank Porreca, James Woods ISBN 0824740319 978-1841844572

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Product details:

ISBN 10: 0824740319

ISBN 13: 978-1841844572 

Author: Kwen-Jen Chang, Frank Porreca, James Woods

The Delta Receptor spans current research in delta receptor biology, pharmacology, physiology, and chemistry to identify, advance, and inspire the development of novel drug candidates. It demonstrates the potential significance and impact of the delta receptor in the therapy and treatment of medical conditions such as pain, gastrointestinal disorders, bladder dysfunction, and depression, as well as heart attack prevention. This reference examines the pathophysiological functions and mechanisms of receptor-selective drugs. Documenting key advances in the field, The Delta Receptor represents the most comprehensive and up-to-date studies on receptor applications currently available.

Table of contents:

PART 1 – The Delta Receptor
CHAPTER 1 – History of Delta Receptors
CHAPTER 2 – Cloning of Delta Opioid Receptors
CHAPTER 3 – Cloning and Expression of the Human Delta Opioid Receptor
CHAPTER 4 – In Vitro and In Vivo Mutagenesis: Insights into Delta Receptor Structure and Function
CHAPTER 5 – Delta Opioid Receptor Signaling and Trafficking
CHAPTER 6 – Delta Opioid Receptors and G Proteins
CHAPTER 7 – Transcriptional Regulation of Delta Opioid Receptor Gene

PART 2 – Delta Ligands
CHAPTER 8 – Benzhydrylpiperazines as Nonpeptidic Delta Opioid Receptor Ligands
CHAPTER 9 – Delta-Selective Ligands Related to Naltrindole
CHAPTER 10 – Endogenous Peptides for Delta Opioid Receptors and Analogues
CHAPTER 11 – Deltorphins
CHAPTER 12 – Opioid Peptide-Derived Delta Antagonists, Inverse Agonists, and Mixed Mu Agonists/Delta Antagonists
CHAPTER 13 – Inverse Agonism at the Delta Opioid Receptors
CHAPTER 14 – Mixed Opioid Receptor Agonists as a New Class of Agents for the Treatment of Moderate to Severe Pain
CHAPTER 15 – Biphalin: A Multireceptor Opioid Ligand
CHAPTER 16 – Binding and Activity of Opioid Ligands at the Cloned Human Delta, Mu, and Kappa Receptors
CHAPTER 17 – Inhibitors of Enkephalin-Inactivating Enzymes and Delta Opioid Responses

PART 3 – Pharmacology and Physiology
CHAPTER 18 – The Delta Opioid Receptor Subtypes and Pain Modulation
CHAPTER 19 – Delta Opioid Receptor-Mediated Antinociception/Analgesia
CHAPTER 20 – Antidepressant-like Effects of Delta Opioid Receptor Agonists
CHAPTER 21 – Mu-Delta Interactions In Vitro and In Vivo
CHAPTER 22 – Delta Opioids and Immune Function
CHAPTER 23 – Delta Opioids and Substance Abuse
CHAPTER 24 – Delta Opioid Receptors in the Gastrointestinal Tract
CHAPTER 25 – Cardioprotection and Delta Opioid Receptors
CHAPTER 26 – The Delta Opioid Receptor and Brain Pain-Modulating Circuits

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Tags: Kwen Jen Chang, Frank Porreca, James Woods, Delta Receptor