Statistical Population Genomics 1st Edition by Julien Y Dutheil ISBN 1071601989 9781071601983

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ISBN 10: 1071601989 
ISBN 13: 9781071601983
Author: Julien Y Dutheil

This open access volume presents state-of-the-art inference methods in population genomics, focusing on data analysis based on rigorous statistical techniques. After introducing general concepts related to the biology of genomes and their evolution, the book covers state-of-the-art methods for the analysis of genomes in populations, including demography inference, population structure analysis and detection of selection, using both model-based inference and simulation procedures. Last but not least, it offers an overview of the current knowledge acquired by applying such methods to a large variety of eukaryotic organisms. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, pointers to the relevant literature, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Statistical Population Genomics 1st Table of contents:

Part I – Essential Concepts

1. A Population Genomics Lexicon

Part II – Statistical Methods for Analyzing Genomes in Populations
2. Processing and Analyzing Multiple Genome Alignments with MafFilter
3. Data Management and Summary Statistics with PLINK
4. Exploring Population Structure with Admixture Models and Principal Components Analysis
5. Detecting Positive Selection in Populations Using Genetic Data
6. polyDFE: Inferring the Distribution of Fitness Effects and Properties of Beneficial Mutations from Polymorphism Data
7. MSMC and MSMC2: The Multiple Sequentially Markovian Coalescent
8. Ancestral Population Genomics with jOcx: A Coalescent Hidden Markov Model
9. Coalescent Simulation with sprime
10. Inference of Ancestral Recombination Graphs Using ARGweaver

Part III – Advances in Population Genomics
11. Population Genomics of Transitions to Selfing in Brassicaceae Model Systems
12. Genomics of Long- and Short-Term Adaptation in Maize and Teosinte
13. Neurospora from Natural Populations: Population Genomics Insights into the Life History of a Model Microbial Eukaryote
14. Population Genomics of Fungal Plant Pathogens and the Analyses of Rapidly Evolving Genome Compartments
15. Population Genomics on the Fly: Recent Advances in Drosophila
16. Genomic Access to the Diversity of Fishes
17. Avian Population Genomics Taking Off: Latest Findings and Future Prospects
18. Population Genomics of the House Mouse and the Brown Rat
19. Population Genomics in the Great Apes

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Tags: Julien Y Dutheil, Genomics