Sex Determination and Sexual Development 1st Edition by Mark Van Doren ISBN 0123744962 9780123744968

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ISBN 10: 0123744962
ISBN 13: 9780123744968
Author: Mark Van Doren

This volume reviews our current understanding for how sex determination is initiated and how it results in sexual dimorphic development. Chapters discussing work on different model systems provide a basis for understanding similarities that exist between different species. Coverage includes discussion of sexual development of the soma in C. elegans; sexual development of the germline in C. elegans; sexual development of the soma in Drosophila; sexual development of the germline in Drosophila; sexual development of the soma in the mouse; sexual development of the germline in the mouse; control of sex-specific behavior in Drosophila; and control of sex-specific behavior in vertebrates.

Sex Determination and Sexual Development 1st Table of contents:

Chapter 1: Somatic Sexual Differentiation in Caenorhabditis elegans

1. Background

2. Telling One from Two: The Primary Signal

3. The Global Sex Regulatory Pathway

4. Attaining Sexual Dimorphism

5. The Interface Between Sex Determination and Sex Differentiation

6. Something Old, Something New: Conservation of Nematode Sexual Regulators

7. The Future
   Acknowledgments
   References

Chapter 2: Sex Determination in the Caenorhabditis elegans Germ Line

1. Nematode Gender: Hermaphrodites, Females, and Males

2. The Core Sex-Determination Pathway

3. Transcriptional Control of Germ Cell Fates by TRA-1

4. Modulating the Sex-Determination Pathway to Create Hermaphrodites

5. Maintaining a Balance Between TRA-2 and FEM-3 Levels

6. Do FOG-1 Levels Control Germ Cell Fates?

7. Mysteries

8. Conclusion
   Acknowledgments
   References

Chapter 3: The Creation of Sexual Dimorphism in the Drosophila Soma

1. Sex Determination

2. The Creation of Sexual Dimorphism

3. A New Look at an Old Problem
   References

Chapter 4: Drosophila Germline Sex Determination: Integration of Germline Autonomous Cues and Somatic Signals

1. Introduction

2. Sexually Dimorphic Niches Regulate Germ Cells

3. Sex Determination in the Germ Cells

4. Germ Cells in a Sex-Mismatched Soma

5. Concluding Remarks
   Acknowledgments
   References

Chapter 5: Sexual Development of the Soma in the Mouse

1. History of Sex Determination in Mammals

2. Molecular Control of Sex Determination

3. Secondary Sex Differentiation

4. Summary
   References

Chapter 6: Development of Germ Cells in the Mouse

1. Origin of the Germ Cell Lineage

2. Specification of Primordial Germ Cells in Mice

3. Migration and Population of the Urogenital Ridge

4. Maintaining Pluripotency in the Germ Cell Lineage

5. Sex-Specific Development of Germ Cells in XX and XY Gonads

6. The Sexually Dimorphic Cell Cycle

7. Epigenetic Regulation in the Mouse Germ Line

8. Sexually Dimorphic Epigenetic Regulation

9. Germ Cells to Stem Cells and Back

10. Conclusions
    Acknowledgments
    References

Chapter 7: The Neuroendocrine Control of Sex-Specific Behavior in Vertebrates: Lessons from Mammals

1. Introduction: General Principles and the Scope of the Chapter

2. Historical Overview

3. Reproductive Behavior in Mammals

4. Reproductive Behaviors in Birds

5. Unanswered Questions and Future Directions

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