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Randomized Phase II Cancer Clinical Trials 1st Edition by Sin Ho Jung ISBN 143987185X 9781439871850

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Randomized Phase II Cancer Clinical Trials 1st Edition Sin-Ho Jung Digital Instant Download

Author(s): Sin-Ho Jung
ISBN(s): 9781439871850, 143987185X
Edition: 1
File Details: PDF, 3.20 MB
Year: 2013
Language: english
SKU: EB-4343446 Category: Tag:

Randomized Phase II Cancer Clinical Trials 1st Edition by Sin Ho Jung – Ebook PDF Instant Download/Delivery: 143987185X, 9781439871850
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ISBN 10: 143987185X
ISBN 13: 9781439871850
Author: Sin Ho Jung

In cancer research, a traditional phase II trial is designed as a single-arm trial that compares the experimental therapy to a historical control. This simple trial design has led to several adverse issues, including increased false positivity of phase II trial results and negative phase III trials. To rectify these problems, oncologists and biosta

Randomized Phase II Cancer Clinical Trials 1st Table of contents:

Chapter 1: Introduction
Chapter 2: Single-Arm Phase II Trial Designs
Chapter 3: Inference on the Binomial Probability in Single-Arm Multistage Clinical Trials
Chapter 4: Single-Arm Phase II Clinical Trials with Time-to-Event Endpoints
Chapter 5: Single-Arm Phase II Trials with Heterogeneous Patient Populations: Binary and Survival Outcomes
Chapter 6: Randomized Phase II Trials for Selection: No Prospective Control Arms
Chapter 7: Randomized Phase II Cancer Clinical Trials with a Prospective Control on Binary Endpoints (I): Two-Sample Binomial Test
Chapter 8: Randomized Phase II Cancer Clinical Trials with a Prospective Control on Binary Endpoints (II): Fisher’s Exact Test
Chapter 9: Randomized Phase II Trials with Heterogeneous Patient Populations: Stratified Fisher’s Exact Test
Chapter 10: Randomized Phase II Clinical Trials Based on Survival Endpoints: Two-Sample Log-Rank Test
Chapter 11: Some Flexible Phase II Clinical Trial Designs

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Tags: Sin Ho Jung, Randomized, Cancer Clinical