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Biochemistry of Signal Transduction and Regulation 2nd Edition by Gerhard Krauss, Bonnie L Cooper, Nancy Schonbrunner ISBN 3527303782 9783527292417

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Protein Phosphorylation 2nd Edition Gerhard Krauss Digital Instant Download

Author(s): Gerhard Krauss, Bonnie L. Cooper, Nancy Schönbrunner
ISBN(s): 9783527292417, 3527303782
Edition: 2
File Details: PDF, 8.05 MB
Year: 2001
Language: english
SKU: EB-1221828 Category: Tags: , ,

Biochemistry of Signal Transduction and Regulation 2nd Edition by Gerhard Krauss, Bonnie L Cooper, Nancy Schonbrunner – Ebook PDF Instant Download/Delivery: 3527303782, 9783527292417
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Product details:

ISBN 10: 3527303782 
ISBN 13: 9783527292417
Author: Gerhard Krauss, Bonnie L Cooper, Nancy Schonbrunner

Now the updated second edition of this bestselling title is available as softcover!

Intracellular signal transduction, regulation of cellular activities, tumor formation, apoptosis – how do they work? These questions have become a central topic in Biology and Biological Chemistry. The importance of this field is mirrored in the 1999 Nobel prize for Physiology that went to G. Blobel for his findings in protein transport regulation.

Over the last decade there has been great progress in the understanding of the molecular basis of signal transduction, and many facts are now basic knowledge for every medicinal chemist, biochemist, and biologist. Since an integral description of cellular regulation and signal transduction is scarcely covered in textbooks, this book fills a real gap. Starting from the principles of gene regulation and regulation of enzyme activity, the topics of this book cover function, structure, and integral construction of signalling pathways plus a detailed description of the various types of carriers such as second messengers, protein kinases, and transmembrane receptors. Central cellular processes like cell cycle regulation, oncogenesis and apoptosis are discussed in light of the properties of the signalling molecules involved. With didactic skill and clarity the author relates the observed biological phenomena to the underlying biochemical processes.
This book is actually two books: Regulation and Signal Transduction.

Biochemistry of Signal Transduction and Regulation 2nd Table of contents:

  1. Basics of Cell Signaling

  2. Structural Properties, Regulation, and Posttranslational Modification of Signaling Proteins

  3. Organization of Signaling

  4. The Regulation of Gene Expression

  5. RNA Processing, Translational Regulation, and RNA Interference

  6. Signaling by Nuclear Receptors

  7. G Protein-Coupled Signal Transmission Pathways

  8. Intracellular Messenger Substances: “Second Messengers”

  9. Ser/Thr-Specific Protein Kinases and Protein Phosphatases

  10. Signal Transmission via Transmembrane Receptors with Tyrosine-Specific Protein Kinase Activity

  11. Signal Transmission via Ras Proteins

  12. Intracellular Signal Transduction: The Protein Cascades of the MAP Kinase Pathways

  13. Membrane Receptors with Associated Tyrosine Kinase Activity

  14. Other Transmembrane Receptor Classes: Signaling by TGF-β Receptors, TNF Receptors, Toll Receptors, and Notch

  15. Cell-Cycle Control by External Signaling Pathways

  16. Malfunction of Signaling Pathways and Tumorigenesis: Oncogenes and Tumor Suppressor Genes

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Tags: Gerhard Krauss, Bonnie L Cooper, Nancy Schonbrunner, Biochemistry