Prognostic and Predictive Factors in Gynecologic Cancers 1st Edition by Charles F Levenback ,Anil Sood ,Karen H Lu ,Robert Coleman ISBN 0415391725 978-0415391726

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Product details: 

ISBN 10:0415391725 

ISBN 13:978-0415391726

Author:Charles F.Levenback ,Anil Sood ,Karen H.Lu ,Robert Coleman

Gynecologic oncology takes a fresh look at a critical aspect of cancer treatment planning. An international team of authors reviews the traditional prognostic and predictive factors such as tumor grade, histologic subtype, and grade and then goes a step further to review the growing number of molecular discoveries that have increasing clinical significance. The book is organized into comprehensive sections on ovarian, endometrial and cervical cancer and includes up to date reviews, newly discovered molecular pathways, genetic markers, molecular imaging techniques, and their relevance to clinical medicine.

Prognostic and Predictive Factors in Gynecologic Oncology is illustrated with over 100 figures and is essential reading for oncologists, translational and basic scientists, as well as fellows, residents and students with a special interest in gynecologic oncology.

Table of contents: 

Part I. Ovary

Clinical predictors of outcome in epithelial ovarian carcinoma

Influence of BRCA1 and BRCA2 on survival

Cell-cycle and apoptotic markers

p53 as a prognostic factor

Use of microarray and CGH technologies for predicting outcome

Angiogenesis and epithelial ovarian carcinoma

Cell-adhesion and matrix-associated proteins in ovarian carcinoma

Effect of immune factors on prognosis

Predictive factors in germ-cell and stromal tumors

Part II. Endometrium
10. Rethinking traditional surgical-pathologic criteria for early stage endometrial cancer: studies of patterns of failure
11. Molecular prognostic and predictive factors in advanced endometrial cancer: implications for therapy
12. Inherited and acquired mismatch repair deficiency
13. Molecular profiling in endometrial cancer: Current research and implications for the future
14. Traditional and molecular predictors of behavior in uterine papillary serous carcinoma and clear cell carcinoma

Part III. Cervical
15. Clinical pathologic predictors in patients with cervical cancer
16. Predictors of radiation sensitivity and resistance
17. Molecular prognostic and predictive factors for cervix cancer
18. Virology in the prevention and management of cervical cancer
19. Molecular imaging for cervical cancer
20. Neuroendocrine cancer of cervix: prognostic and predictive factors
21. Predictive values of sentinel lymph nodes

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Tags: Charles F Levenback, Anil Sood, Karen H Lu, Robert Coleman, Prognostic, Predictive