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Pharmacogenomics in Drug Discovery and Development 2nd Edition by Qing Yan ISBN 1493909568 9781493909568

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Pharmacogenomics in Drug Discovery and Development 2nd Edition Qing Yan (Eds.) Digital Instant Download

Author(s): Qing Yan (eds.)
ISBN(s): 9781493909568, 1493909568
Edition: 2
File Details: PDF, 9.66 MB
Year: 2014
Language: english
SKU: EB-4929874 Category: Tag:

Pharmacogenomics in Drug Discovery and Development 2nd Edition by Qing Yan – Ebook PDF Instant Download/Delivery: 1493909568, 9781493909568
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ISBN 10: 1493909568 
ISBN 13: 9781493909568
Author: Qing Yan

Covering topics from individual molecules to systemic diseases, from basic concepts to advanced technologies, Pharmacogenomics in Drug Discovery and Development , Second Edition provides a practical, state-of-the-art and integrative view of the application of pharmacogenomics in drug discovery and development. A wide range of theoretical and experimental approaches are introduced to meet the problem-solving objectives for understanding the complexity in health and diseases, from laboratory tests to computational analysis. The development of pharmacogenomics represents the evolution of biomedicine from treating the disease itself to treating the malfunction of an individual person, the “root” of diseases. With the change of focus from disease-centered to human-centric medicine, pharmacogenomics brings hope for the transformation from simple disease treatment to accurate prediction and effective prevention. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls.

Pharmacogenomics in Drug Discovery and Development 2nd Table of contents:

  1. From Pharmacogenomics and Systems Biology to Personalized Care: A Framework of Systems and Dynamical Medicine
    Qing Yan
    Pages 3-17

  2. Translational Bioinformatics Approaches for Systems and Dynamical Medicine
    Qing Yan
    Pages 19-34

  3. Whole Blood Transcriptomic Analysis to Identify Clinical Biomarkers of Drug Response
    Grant P. Parnell, David R. Booth
    Pages 35-43

  4. Diagnostic Procedures for Paraffin-Embedded Tissues Analysis in Pharmacogenomic Studies
    Raffaele Palmirotta, Maria Laura De Marchis, Giorgia Ludovici, Patrizia Ferroni, Pasquale Abete, Fiorella Guadagni et al.
    Pages 45-65

  5. Approach to Clinical and Genetic Characterization of Statin-Induced Myopathy
    QiPing Feng
    Pages 67-90

  6. Pharmacogenetics of Membrane Transporters: A Review of Current Approaches
    Tristan M. Sissung, Andrew K. L. Goey, Ariel M. Ley, Jonathan D. Strope, William D. Figg
    Pages 91-120

  7. G Protein-Coupled Receptor Accessory Proteins and Signaling: Pharmacogenomic Insights
    Miles D. Thompson, David E. C. Cole, Pedro A. Jose, Peter Chidiac
    Pages 121-152

  8. G Protein-Coupled Receptor Mutations and Human Genetic Disease
    Miles D. Thompson, Geoffrey N. Hendy, Maire E. Percy, Daniel G. Bichet, David E. C. Cole
    Pages 153-187

  9. Pharmacogenetics of the G Protein-Coupled Receptors
    Miles D. Thompson, David E. C. Cole, Valerie Capra, Katherine A. Siminovitch, G. Enrico Rovati, W. McIntyre Burnham et al.
    Pages 189-242

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Tags: Qing Yan, Pharmacogenomics, Drug Discovery