Organ Development 1st Edition by Deneen Wellik ISBN 0128104902 9780128104903
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ISBN 10: 0128104902
ISBN 13: 9780128104903
Author: Deneen Wellik
Organ Development, Volume 132, the latest release in the Current Topics in Developmental Biology series, highlights new advances in the field, with this new volume presenting interesting chapter written by an international board of authors. This volume highlights cogent reviews of the development, maintenance and regeneration/repair of several organ systems, from eye to kidney, to the musculoskeletal system. Many reviews highlight new techniques or technologies that are currently pushing the field. The role of both embryonic and adult stem cells are highlighted and senior authors are all women scientists.
- Provides the authority and expertise of leading contributors from an international board of author
- Presents the latest release in this series
- Updated release includes the latest information on organ development
Organ Development 1st Table of contents:
Chapter One: Chasing Mavericks: The quest for defining developmental waves of hematopoiesis
Abstract
1 Introduction
2 HSC emergence: Where, when, and how?
3 Molecular regulation of HSC specification
4 Phenotypic and functional heterogeneity within the HSPC pool
5 Purpose of developmental waves
6 Conclusion and future directions
Acknowledgments
Author contributions
Competing interests
Chapter Two: Signals and forces shaping organogenesis of the small intestine
Abstract
1 Generation and growth of the intestinal tube
2 Patterning and regionalization
3 Villus development
4 Making crypts
5 Organoid systems to study intestinal development
6 Summary
Chapter Three: Consider the lung as a sensory organ: A tip from pulmonary neuroendocrine cells
Abstract
1 Overview: Lung as a sensory organ
2 PNEC lineage origin and specification
3 PNEC innervation
4 PNECs in lung development
5 PNEC function as progenitors and progenitor niches
6 PNEC function in response to airway inputs
7 PNECs in chronic lung diseases
8 Pulmonary neuroendocrine cells in cancer
9 Concluding remarks
Chapter Four: Molecular regulation of mammalian hepatic architecture
Abstract
1 Hepatic specification
2 Hepatic architecture
3 Hepatocyte cell fate decision
4 Cholangiocyte cell fate decision and intrahepatic bile duct morphogenesis
5 Conclusions
Chapter Five: Connecting muscle development, birth defects, and evolution: An essential role for muscle connective tissue
Abstract
1 Introduction
2 Axial muscle
3 Cranial muscle
4 Limb muscle
5 Diaphragm
6 Conclusion
Chapter Six: Vascularizing organogenesis: Lessons from developmental biology and implications for regenerative medicine
Abstract
1 Introduction
2 EC development, heterogeneity, and the challenges we face
3 Vascular morphogenesis in specific organ systems
4 “Therapeutic” development: Using development to guide regenerative medicine
5 Concluding remarks
Acknowledgments
Chapter Seven: Pancreas organogenesis: The interplay between surrounding microenvironment(s) and epithelium-intrinsic factors
Abstract
1 Overview of embryonic pancreas development
2 The pancreatic microenvironment
3 Implications for directed differentiation of pluripotent stem cells into pancreatic β-cells
4 Open questions and future directions
Acknowledgments
Chapter Eight: Gametogenesis: A journey from inception to conception
Abstract
1 Germ cell specification and gonadal morphogenesis
2 Germ cell sex determination
3 Oogenesis
4 Spermatogenesis
5 Epigenetic reprogramming in PGCs, gametes, and early embryos
6 In vitro gametogenesis
7 Conclusion
Chapter Nine: Genetics of scapula and pelvis development: An evolutionary perspective
Abstract
1 Introduction
2 Scapula development
3 Pelvic development
4 Genetic networks
5 Conclusions and future directions
Acknowledgments
Chapter Ten: Eye organogenesis: A hierarchical view of ocular development
Abstract
1 Introduction
2 Cornea
3 Lens
4 Eye field specification
5 Optic vesicle evagination
6 Optic vesicle/cup patterning and morphogenesis
7 Ciliary body and iris
8 Neural retina
9 Retina pigmented epithelium
10 Summary
Chapter Eleven: Fluid forces shape the embryonic heart: Insights from zebrafish
Abstract
1 Introduction
2 Examination of fluid forces in zebrafish
3 Hemodynamics and cardiovascular morphogenesis
4 Summary and future directions
Chapter Twelve: New perspectives on the mechanisms establishing the dorsal-ventral axis of the spinal cord
Abstract
1 Functional organization of the adult spinal cord
2 The specification of dorsal and ventral patterning in the spinal cord
3 Looking ahead: What does knowledge of these manipulations mean for spinal cord regeneration?
Chapter Thirteen: Development, repair, and regeneration of the limb musculoskeletal system
Abstract
1 Introduction
2 Development
3 Establishing limb pattern and morphology
4 Injury repair and regeneration
5 Musculoskeletal stromal progenitor and stem cells
6 Conclusion/perspective
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Tags: Deneen Wellik, Organ Development