Novel Vaccination Strategies 1st Edition by Stefan H E Kaufmann ISBN 3527305238 978-3527305230
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Product details:
ISBN 10:3527305238
ISBN 13:978-3527305230
Author:Stefan H.E.Kaufmann
The protection mode of most available vaccines is based on antibody responses. Since efficient immune responses to many pathogens rely on activating all arms of the immune system, traditional vaccine development does not provide efficient protection against many diseases. Novel vaccination strategies need to allow presentation of antigens that activate the full array of the immune response in the right composition and should prevent pathogen entry by mobilizing the mucosal immune response. New technological advances optimize the immunogenicity of ‘live’ and sub-unit vaccines.
This book offers an interdisciplinary overview on research and future strategies for rational vaccine
design based on recent developments in molecular biology and immunology. It covers new aspects of the immunological interplay between prokaryotic and eukaryotic systems as well as achievements in the development of novel vaccine candidates.
Chapters on edible vaccines, on vaccines against bioterror agents and on economical and safety aspects of novel vaccine development round off this title.
Novel Vaccination Strategies 1st Table of contents:
- Challenges for the Vaccine Developer, Including Correlates of Protection
G. J. V. Nossal - Shaping Adaptive Immunity against Pathogens: The Contribution of Innate Immune Responses
Stefan Ehlers, Silvia Bulfone-Paus - Adjuvant-Induced Th2- and Th1-Dominated Immune Responses in Vaccination
James M. Brewer, Kevin G. J. Pollock - Memory
Alexander Ploss, Eric G. Pamer - T Cell-Based Vaccines
Katharina M. Huster, Kristen M. Kerksiek, Dirk H. Busch - Microbial Adjuvants
Klaus Heeg, Stefan Zimmermann, Alexander Dalpke - Host-Derived Adjuvants
Norbert Hilf, Markus Radsak, Hansjörg Schild - Microparticles as Vaccine Adjuvants and Delivery Systems
Derek T. O’Hagan, Manmohan Singh - Liposomes and ISCOMs
Gideon Kersten, Debbie Drane, Martin Pearse, Wim Jiskoot, Alan Coulter - Virosomal Technology and Mucosal Adjuvants
Jean-François Viret, Christian Moser, Faiza Rharbaoui, Ian C. Metcalfe, Carlos A. Guzmán - Classical Bacterial Vaccines
Thomas Ebensen, Claudia Link, Carlos A. Guzmán - Subunit Vaccines and Toxoids
Maria Lattanzi, Giuseppe Del Giudice, Rino Rappuoli - Engineering Virus Vectors for Subunit Vaccines
Joseph Patrick Nkolola, Tomas Hanke - Update on Antiviral DNA Vaccine Research (2000–2003)
Daniel Franke, Jovan Pavlovic, Tillmann S. Utesch, Max von Kleist, Jan Schultz, Guenter Dollenmaier, Karin Moelling - Live Recombinant Bacterial Vaccines
Simon Clare, Gordon Dougan - Mucosal Vaccination
Wieslawa Olszewska, Peter J. M. Openshaw - Passive Vaccination and Antidotes: A Novel Strategy for Generation of Wide-Spectrum Protective Antibodies
Antonio Cassone, Luciano Polonelli - Plant-Based Oral Vaccines
Kan Wang, Rachel Chikwamba, Joan Cunnick - Virus-Like Particles: Combining Innate and Adaptive Immunity for Effective Vaccination
Martin F. Bachmann, Gary T. Jennings - Helicobacter pylori
Paolo Ruggiero, Rino Rappuoli, Giuseppe Del Giudice - Novel Vaccination Strategies against Tuberculosis
Prof. Dr. Stefan H. E. Kaufmann - Rationale for Malaria Vaccine Development
Allan Saul, Victor Nussenzweig, Ruth S. Nussenzweig - Vaccine for Specific Targets: HIV
R. Kay, E. G.-T. Wee, A. J. McMichael - Vaccines against Bioterror Agents
Karen L. Elkins, Drusilla L. Burns, Michael P. Schmitt, Jerry P. Weir - Imperfect Vaccines and the Evolution of Pathogen Virulence
Paul W. Ewald - Cost-Effectiveness of Vaccinations
Thomas D. Szucs - Immunological Safety of Vaccines: Facts, Hypotheses and Allegations
Michel Goldman, Paul-Henri Lambert
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Tags: Stefan H E Kaufmann, Novel, Vaccination, Strategies