Nickel and the Skin Absorption Immunology Epidemiology and Metallurgy 1st Edition by Jurij Hostynek, Howard Maibach, Flint, Katherine Reagan, Cutler, Camera, Picardo – Ebook PDF Instant Download/Delivery: 0367250527 ,9780367250522
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ISBN 10: 0367250527
ISBN 13: 9780367250522
Author: Jurij Hostynek, Howard Maibach, Flint, Katherine Reagan, Cutler, Camera, Picardo
First published 2002, Allergic contact dermatitis from nickel is a continuing and increasing health problem. Nickel dermatitis may occur in sensitized individuals following contact with nickel-containing items such as jewelry, zippers, buttons, and other objects; by nickel leaching from implants and prostheses; and following occupational exposures. Although the most common of the health effects associated with exposure to nickel, the skin penetration of nickel and its compounds is poorly understood.
Nickel and the Skin: Absorption, Immunology, Epidemiology, and Metallurgy gives an extensive, updated review of major topics and new topics, and covers material progress in the field of nickel hypersensitivity. Its content complements the mandate of NiPERA, the Nickel Producers Environmental Research Association, which is to promote the health and safety of those exposed to nickel or nickel containing products in the workplace and general environment.
Many books on the toxicology of metals discuss nickel and its alloys in general terms. This one provides you with in-depth information on the causes, diagnosis, prognosis, and prevention, all in one source. Nickel and the Skin: Absorption, Immunology, Epidemiology, and Metallurgy provides a guide to the evaluation and treatment of what has become the most common cause of allergic contact dermatitis.
Nickel and the Skin Absorption Immunology Epidemiology and Metallurgy 1st Edition Table of contents:
Part I: Introduction to Nickel and its Role in Human Health
Chapter 1: Overview of Nickel and its Uses
- Introduction to Nickel: A Versatile Metal
- Industrial Applications of Nickel
- Sources of Nickel Exposure in Everyday Life
Chapter 2: Nickel and Human Biology
- Nickel’s Role in the Human Body
- Absorption and Metabolism of Nickel
- Nickel’s Toxicity and Health Effects
- The Mechanism of Nickel-Induced Health Issues
Part II: Nickel Absorption and Skin Penetration
Chapter 3: Mechanisms of Skin Absorption of Nickel
- Structure of the Skin and its Barrier Functions
- How Nickel Penetrates the Skin
- Factors Affecting Nickel Absorption Through the Skin
- Role of Skin pH, Occlusion, and Skin Integrity
Chapter 4: Experimental Methods for Studying Nickel Absorption
- In Vitro Models of Skin Penetration
- Use of Animal Models in Skin Absorption Studies
- Non-invasive Techniques for Measuring Skin Nickel Content
Part III: Nickel and Immune Responses
Chapter 5: Nickel-Induced Allergic Contact Dermatitis
- Pathophysiology of Nickel Allergy
- Mechanisms of Nickel Sensitization
- Immunological Mechanisms in Nickel-Induced Skin Reactions
Chapter 6: Other Immunological Effects of Nickel
- Nickel and Systemic Immune Responses
- Nickel’s Role in Autoimmune Diseases
- Nickel’s Effects on the Respiratory and Cardiovascular Systems
Chapter 7: Clinical Diagnosis and Management of Nickel Sensitization
- Diagnosis of Nickel Allergy: Patch Testing and Other Methods
- Treatment and Management of Nickel Allergies
- Preventive Measures and Recommendations for Sensitive Individuals
Part IV: Epidemiology of Nickel Exposure
Chapter 8: Global Distribution of Nickel Exposure
- Occupational vs. Environmental Exposure
- Nickel in the Air, Water, and Food
- Population at Risk for Nickel Sensitization
Chapter 9: Epidemiological Studies of Nickel Allergy
- Prevalence of Nickel Sensitization Worldwide
- Demographics and Risk Factors for Nickel Allergy
- Trends in Nickel Exposure and Health Outcomes
Chapter 10: Case Studies and Regional Variations
- Case Studies of Nickel Exposure in Occupational Settings
- Regional Differences in Nickel Sensitization Rates
- Impact of Environmental Policies on Nickel Exposure
Part V: Nickel in Metallurgy and Environmental Impact
Chapter 11: Nickel Production and Environmental Concerns
- Mining and Refining of Nickel
- Environmental Impact of Nickel Extraction
- Nickel Waste Management and Pollution Control
Chapter 12: Sustainable Use and Alternatives to Nickel
- Reducing Environmental Impact in Nickel Mining
- Recycling of Nickel and Sustainable Practices in Industry
- Potential Alternatives to Nickel in Various Applications
Part VI: Conclusion and Future Directions
Chapter 13: The Future of Nickel Research and Public Health
- Emerging Studies on Nickel and Health
- New Techniques for Reducing Nickel Exposure
- Policy and Regulation Changes in Response to Nickel Health Risks
Chapter 14: Final Thoughts on Nickel Sensitization and Its Management
- Summary of Key Findings
- Recommendations for Clinical and Environmental Management
- Future Research Directions
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Jurij Hostynek,Howard Maibach,Flint,Katherine Reagan,Cutler,Camera,Picardo,Skin Absorption