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Neuroimaging in Developmental Clinical Neuroscience 1st Edition by Judith M Rumsey, Monique Ernst ISBN 0521883571 9780511757402

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Neuroimaging in Developmental Clinical Neuroscience 1st Edition Judith M. Rumsey (Editor) Digital Instant Download

Author(s): Judith M. Rumsey (editor), Monique Ernst (editor)
ISBN(s): 9780511757402, 0521883571
Edition: 1
File Details: PDF, 29.38 MB
Year: 2009
Language: english
SKU: EB-2226974 Category: Tags: ,

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ISBN 10: 0521883571 
ISBN 13: 9780511757402
Author: Judith M Rumsey, Monique Ernst

Modern neuroimaging offers tremendous opportunities for gaining insights into normative development and a wide array of developmental neuropsychiatric disorders. Focusing on ontogeny, this text covers basic processes involved in both healthy and atypical maturation, and also addresses the range of neuroimaging techniques most widely used for studying children. This book will enable you to understand normative structural and functional brain maturation and the mechanisms underlying basic developmental processes; become familiar with current knowledge and hypotheses concerning the neural bases of developmental neuropsychiatric disorders; and learn about neuroimaging techniques, including their unique strengths and limitations. Coverage includes normal developmental processes, atypical processing in developmental neuropsychiatric disorders, ethical issues, neuroimaging techniques and their integration with psychopharmacologic and molecular genetic research approaches, and future directions. This comprehensive volume is an essential resource for neurologists, neuropsychologists, psychiatrists, pediatricians, and radiologists concerned with normal development and developmental neuropsychiatric disorders.

Neuroimaging in Developmental Clinical Neuroscience 1st Table of contents:

Section 1: Normal Developmental Processes

1. Morphological Development of the Brain: What Has Imaging Told Us?

  • 1.1 Overview of Brain Development

  • 1.2 Neuroimaging Insights into Brain Structure and Growth

  • 1.3 Longitudinal Studies on Brain Morphology

  • 1.4 Key Findings and Implications for Developmental Neuroscience

2. Neural Correlates of the Development of Cognitive Control

  • 2.1 Defining Cognitive Control in Development

  • 2.2 The Role of Prefrontal Cortex in Cognitive Control

  • 2.3 Functional and Structural Imaging of Cognitive Control Networks

  • 2.4 Developmental Trajectories of Cognitive Control in Childhood and Adolescence

3. Neurobiology of Emotion Regulation in Children and Adults

  • 3.1 Mechanisms of Emotion Regulation

  • 3.2 Developmental Changes in Brain Regions Involved in Emotion Regulation

  • 3.3 Neuroimaging Evidence of Emotion Regulation in Children and Adults

  • 3.4 The Role of the Prefrontal Cortex and Limbic System

4. Goal-Directed Behavior: Evolution and Ontogeny

  • 4.1 Evolutionary and Developmental Perspectives on Goal-Directed Behavior

  • 4.2 Brain Mechanisms Underpinning Motivation and Goal Pursuit

  • 4.3 Neuroimaging Insights into Goal-Directed Behavior Across the Lifespan

  • 4.4 Implications for Developmental Neuroscience and Clinical Practice

5. Charting Brain Mechanisms for the Development of Social Cognition

  • 5.1 The Social Brain: Key Regions and Networks

  • 5.2 Developmental Changes in Social Cognitive Abilities

  • 5.3 Neuroimaging Studies of Theory of Mind and Empathy

  • 5.4 Social Cognition in Adolescence and Early Adulthood

6. Language and the Developing Brain: Insights from Neuroimaging

  • 6.1 Neural Basis of Language Acquisition

  • 6.2 Neuroimaging of Language Development in Children

  • 6.3 Brain Networks Involved in Language Processing

  • 6.4 Insights into Bilingualism and Language Disorders

Section 2: Atypical Processes in Developmental Neuropsychiatric Disorders

7. A Pathophysiology of Attention Deficit/Hyperactivity Disorder: Clues from Neuroimaging

  • 7.1 Overview of ADHD and Brain Mechanisms

  • 7.2 Structural and Functional Neuroimaging Findings in ADHD

  • 7.3 Brain Networks Implicated in Attention and Impulsivity

  • 7.4 Neuroimaging Biomarkers for Diagnosis and Treatment

8. Brain Imaging of Autism Spectrum Disorders

  • 8.1 Neuroanatomical and Functional Findings in Autism

  • 8.2 Alterations in Brain Connectivity in ASD

  • 8.3 Insights into Sensory Processing and Social Cognition

  • 8.4 The Role of Early Neuroimaging in ASD Diagnosis

9. Neuroimaging of Schizophrenia and Its Development

  • 9.1 Developmental Origins of Schizophrenia

  • 9.2 Brain Structure and Function in Early-onset Schizophrenia

  • 9.3 Neuroimaging of Psychosis Risk and Progression

  • 9.4 Brain Connectivity and Cognitive Decline in Schizophrenia

10. Cortico-Limbic Development in Bipolar Disorder: A Neuroimaging View

  • 10.1 Brain Circuitry in Bipolar Disorder

  • 10.2 Structural and Functional Brain Changes in Mood Disorders

  • 10.3 Cortico-limbic Dysregulation and Emotional Dysregulation

  • 10.4 Neuroimaging Biomarkers for Bipolar Disorder

11. Anxiety and Depressive Disorders

  • 11.1 Neurobiological Mechanisms of Anxiety and Depression

  • 11.2 Imaging Anxiety Networks in Children and Adolescents

  • 11.3 Structural and Functional Brain Changes in Depression

  • 11.4 Neuroimaging in the Context of Anxiety and Depression Treatment

12. Disturbances of Fronto-Striatal Circuits in Tourette Syndrome and Obsessive-Compulsive Disorder

  • 12.1 Brain Mechanisms of Habitual and Compulsive Behavior

  • 12.2 Neuroimaging of Fronto-Striatal Pathways in Tic and OCD Disorders

  • 12.3 Connectivity and Dysfunction in Tourette Syndrome

  • 12.4 Imaging Approaches to Understanding Tic Disorders

13. From Genes to Brain to Behavior: The Case of Fragile X Syndrome

  • 13.1 Genetic Basis of Fragile X Syndrome

  • 13.2 Neuroimaging Findings in Fragile X Syndrome

  • 13.3 Brain Development and Behavioral Manifestations

  • 13.4 Neuroimaging as a Diagnostic Tool in Fragile X

14. Alcohol Exposure and the Developing Human Brain

  • 14.1 The Impact of Prenatal Alcohol Exposure on Brain Development

  • 14.2 Neuroimaging of Fetal Alcohol Spectrum Disorders (FASD)

  • 14.3 Structural and Functional Alterations in Brain Regions Affected by Alcohol

  • 14.4 Interventions and Neuroimaging Biomarkers for FASD

15. Neuroimaging as a Tool for Unlocking Developmental Pathophysiology in Anorexia and Bulimia Nervosa

  • 15.1 Neurobiological Insights into Eating Disorders

  • 15.2 Brain Structural and Functional Changes in Anorexia and Bulimia

  • 15.3 The Role of Reward Systems and Executive Control

  • 15.4 Neuroimaging in Treatment Planning and Monitoring

Section 3: Ethical Issues

16. Legal and Ethical Considerations in Pediatric Neuroimaging Research

  • 16.1 Ethical Dilemmas in Pediatric Neuroimaging Studies

  • 16.2 Informed Consent and Assent in Children

  • 16.3 Privacy and Data Protection in Neuroimaging Research

  • 16.4 Balancing Research Benefits and Risks in Pediatric Populations

Section 4: Techniques and Integration with Other Research Approaches

17. BOLD fMRI: An Update with Emphasis on Pediatric Applications

  • 17.1 Principles of BOLD fMRI and its Relevance to Development

  • 17.2 Pediatric Applications and Challenges in fMRI Research

  • 17.3 Advancements in fMRI Techniques for Children

  • 17.4 Clinical and Research Applications in Developmental Disorders

18. Magnetic Resonance Spectroscopy: Methods and Applications in Developmental Clinical Neuroscience

  • 18.1 Overview of MR Spectroscopy (MRS)

  • 18.2 MRS in Developmental Brain Disorders

  • 18.3 Metabolites and Neurochemical Changes in Development

  • 18.4 Clinical Relevance of MRS in Pediatric Populations

19. Diffusion Tensor Imaging in Developmental Clinical Neuroscience

  • 19.1 Principles of Diffusion Tensor Imaging (DTI)

  • 19.2 White Matter Development and Brain Connectivity

  • 19.3 DTI Applications in Neurodevelopmental and Psychiatric Disorders

  • 19.4 Using DTI to Investigate Brain Plasticity

20. Arterial Spin Labeling Perfusion Magnetic Resonance Imaging in Developmental Neuroscience

  • 20.1 Principles and Applications of Arterial Spin Labeling (ASL)

  • 20.2 Measuring Cerebral Blood Flow in Development

  • 20.3 ASL in Neurodevelopmental and Psychiatric Disorders

  • 20.4 Challenges and Future Directions in Perfusion Imaging

21. Neuroimaging of Treatment Effects in Developmental Neuropsychiatric Disorders

  • 21.1 Assessing Treatment Responses Using Neuroimaging

  • 21.2 Imaging Brain Changes in Response to Medications and Therapies

  • 21.3 Predicting Treatment Outcomes with Neuroimaging Biomarkers

  • 21.4 Clinical Implications for Pediatric Populations

22. Functional Alleles, Neuroimaging, and Intermediate Phenotypes in the Deconstruction of Complex Behavioral Variation

  • 22.1 The Role of Genetic Variation in Brain Function

  • 22.2 Intermediate Phenotypes: Bridging Genetics and Brain Imaging

  • 22.3 Neuroimaging of Functional Alleles and Behavioral Outcomes

  • 22.4 Implications for Psychiatric and Neurodevelopmental Disorders

Section 5: Progress and Future Directions

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Tags: Judith M Rumsey, Monique Ernst, Neuroimaging