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Neurobiology of Mental Illness 4th Edition by Dennis S Charney, Joseph D Buxbaum, Pamela Sklar, Eric J Nestler ISBN 0199934959 9780199934959

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Neurobiology of Mental Illness 4th Edition Dennis S. Charney Digital Instant Download

Author(s): Dennis S. Charney, Joseph D. Buxbaum, Pamela Sklar, Eric J. Nestler
ISBN(s): 9780199934959, 0199934959
Edition: 4
File Details: PDF, 26.99 MB
Year: 2013
Language: english
SKU: EB-5220692 Category: Tags: , , ,

Neurobiology of Mental Illness 4th Edition by Dennis S Charney, Joseph D Buxbaum, Pamela Sklar, Eric J Nestler – Ebook PDF Instant Download/Delivery: 0199934959, 9780199934959
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ISBN 10: 0199934959 
ISBN 13: 9780199934959
Author: Dennis S Charney, Joseph D Buxbaum, Pamela Sklar, Eric J Nestler

Our understanding of the neurobiological basis of psychiatric disease has accelerated in the past five years. The fourth edition of Neurobiology of Mental Illness has been completely revamped given these advances and discoveries on the neurobiologic foundations of psychiatry. Like its predecessors the book begins with an overview of the basic science. The emerging technologies in Section 2 have been extensively redone to match the progress in the field including new chapters on the applications of stem cells, optogenetics, and image guided stimulation to our understanding and treatment of psychiatric disorders. Sections 3 through 8 pertain to the major psychiatric syndromes-the psychoses, mood disorders, anxiety disorders, substance use disorders, dementias, and disorders of childhood-onset. Each of these sections includes our knowledge of their etiology, pathophysiology, and treatment. The final section discusses special topic areas including the neurobiology of sleep, resilience, social attachment, aggression, personality disorders and eating disorders. In all, there are 32 new chapters in this volume including unique insights on DSM-5, the Research Domain Criteria (RDoC) from NIMH, and a perspective on the continuing challenges of diagnosis given what we know of the brain and the mechanisms pertaining to mental illness. This book provides information from numerous levels of analysis including molecular biology and genetics, cellular physiology, neuroanatomy, neuropharmacology, epidemiology, and behavior. In doing so it translates information from the basic laboratory to the clinical laboratory and finally to clinical treatment. No other book distills the basic science and underpinnings of mental disorders and explains the clinical significance to the scope and breadth of this classic text. The result is an excellent and cutting-edge resource for psychiatric residents, psychiatric researchers and doctoral students in neurochemistry and the neurosciences.

Neurobiology of Mental Illness 4th Table of contents:

Chapter 1: Introduction to Neurobiology and Mental Illness

  • Historical Perspectives

  • Overview of Brain Structure and Function

  • Neurobiology of Psychiatric Disorders

Chapter 2: Genetics and Epigenetics in Mental Illness

  • Genetic Contributions to Mental Disorders

  • Epigenetic Mechanisms

  • Gene-Environment Interactions

Chapter 3: Neurodevelopmental Basis of Mental Illness

  • Brain Development and Critical Periods

  • Neurodevelopmental Disorders

  • Impact of Early Life Stress

Chapter 4: Neurotransmitter Systems and Mental Illness

  • Dopamine and Psychosis

  • Serotonin and Mood Disorders

  • Glutamate, GABA, and Other Neurotransmitters

Chapter 5: Neurocircuitry and Brain Networks

  • Functional Brain Circuits in Psychiatric Disorders

  • Imaging Studies and Biomarkers

  • Connectivity and Network Dysregulation

Chapter 6: Mood Disorders

  • Neurobiology of Depression

  • Bipolar Disorder Mechanisms

  • Treatment Implications

Chapter 7: Schizophrenia and Psychotic Disorders

  • Pathophysiology

  • Cognitive and Negative Symptoms

  • Neurobiological Models

Chapter 8: Anxiety and Stress-Related Disorders

  • Fear Circuits

  • PTSD Neurobiology

  • Anxiety Disorders

Chapter 9: Substance Use Disorders

  • Neurobiology of Addiction

  • Reward Pathways

  • Neuroadaptive Changes

Chapter 10: Neuroinflammation and Mental Illness

  • Immune System and Brain

  • Role of Inflammation in Psychiatric Disorders

  • Therapeutic Targets

Chapter 11: Neurodegeneration and Psychiatric Symptoms

  • Overlaps with Dementia and Parkinson’s Disease

  • Cognitive and Behavioral Changes

Chapter 12: Advances in Treatment and Future Directions

  • Pharmacotherapy

  • Neuromodulation Techniques

  • Personalized Medicine

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Tags: Dennis S Charney, Joseph D Buxbaum, Pamela Sklar, Eric J Nestler, Neurobiology, Mental Illness