Hormone Replacement Therapy and The Brain Controversial Issues in Climacteric Medicine Series 1st Edition by Andrea R Genazzani ISBN 1842141686 978-1842141687

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Product details:

ISBN 10:  1842141686 

ISBN 13: 978-1842141687

Author: Andrea R. Genazzani 

In recent years there has been increased interest in the possibility that hormone replacement therapy may have a significant impact on neurological function in the aging female. It has been hypothesized that estrogens may even have a protective role in the onset of Alzheimer’s or other dementias. This volume draws together leading experts to review the existing scientific data and present a consensus view that will be a practical aid to clinicians. The book offers a state-of-the-art summary of current knowledge that gives readers a better understanding of the potential benefits of hormone therapy when treating Alzheimer’s and other dementias.

Table of contents: 

Section I: Brain cells and the aging process

1. Glia and extracellular space in the aging brain

Section II: The impact of aging on integrated brain function
2. Estrogen regulation of mitochondrial function and impact of the aging process
3. The immune system, estrogen and brain aging
4. Brain phenotype of the aromatase knock-out mouse
5. Neurosteroids and γ-aminobutyric acid type A receptor function and plasticity

Section III: Neurobiology of steroids and their receptors
6. Sex hormone receptors in the human hypothalamus in different stages of human life
7. Progesterone in the nervous system: an old player in new roles
8. Testosterone metabolism and its effects on glial cells of the central nervous system

Section IV: Central symptoms of menopause
9. Physiological mechanisms of menopausal hot flushes
10. Menopause, hormone replacement therapy and sleep disturbance
11. Sex hormones and headache

Section V: Menopause: mood and behavior
12. Gender differences in affective disorders: a brief review
13. Androgen-insufficiency syndrome and women’s sexuality

Section VI: Hormone replacement therapy: effects on mood and behavior
14. Estrogen replacement therapy and mood: the brain as a target tissue of sex steroids
15. Progestogens and menopause: effect on mood and quality of life
16. Androgen replacement therapy: a new piece of the mosaic

Section VII: Menopause, hormone replacement therapy and psychiatric diseases
17. The perimenopause and depressive illness
18. Depression in menopausal women
19. Gender differences in anxiety disorders: the role of female hormones
20. Schizophrenia, menopause and estrogen replacement therapy: a review

Section VIII: Cognition, memory, menopause and aging
21. Unsolved and controversial issues regarding neuroprotection by estrogen
22. Sex hormone receptor polymorphisms and cognitive impairment in older men and women
23. Menopause risk factor for memory loss or Alzheimer’s disease?

Section IX: Hormone replacement therapy and neurological disorders
24. Depression, aging and the metabolic syndrome
25. Hormone replacement therapy and risk of Parkinson’s disease
26. Hormone replacement therapy and Alzheimer’s disease

Section X: Selective aspects of specific therapies
27. Menopause: it’s all in the brain
28. Women, hormones and depression
29. Methodological pitfalls in the study of estrogen effects on cognition and brain function
30. Safety and tolerability of transdermal testosterone therapy versus placebo in surgically menopausal women receiving oral or transdermal estrogen
31. Selective estrogen receptor modulators: effects in the brain

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Tags: Andrea R Genazzani, Hormone Replacement Therapy, Brain, Controversial Issues, Climacteric Medicine