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Haemostasis Methods and Protocols 1st Edition by Paul Monagle ISBN 1493961020 978-1493961023

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Haemostasis Methods and Protocols 1st Edition Anthony K. C. Chan Digital Instant Download

Author(s): Anthony K. C. Chan, Nethnapha Paredes (auth.), Paul Monagle (eds.)
ISBN(s): 9781627033398, 1627033394
Edition: 1
File Details: PDF, 5.12 MB
Year: 2013
Language: english
SKU: EB-11849896 Category: Tags: , ,

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Product details:

ISBN 10: 1493961020

ISBN 13: 978-1493961023 

Author: Paul Monagle

The haemostatic system is one the most important physiological systems for maintaining health and well being, and thus the investigation of the haemostatic system remains a research priority. Disturbances of the haemostatic system in the broader sense, such as heart disease and strokes, arguably constitute the single greatest contribution to non-infectious mortality in the world today. Therefore, understanding the laboratory methods to assess the haemostatic system is vital for the practice of complex clinical medicine.In Haemostasis: Methods and Protocols, experts in the field address the major components of the haemostatic system, general principles of haemostatic testing, and techniques used to assess various aspects of the haemostatic system, grouped according to their functional indications. Written in the successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls.

Authoritative and easily accessible, Haemostasis: Methods and Protocols provides an ideal guide to scientists of all backgrounds and serves an urgent need for further research to develop superior methods of assessing the haemostatic system in humans.

Table of contents:

  1. The Coagulation System in Humans

  2. Platelet Physiology

  3. The Role of the Blood Vessel Wall

  4. Specimen Requirements for the Haemostasis Laboratory

  5. Principles of Haemostasis Tests

  6. Reference Ranges of Coagulation Tests

  7. Lupus Anticoagulant Testing

  8. Activated Partial Thromboplastin Time (APTT)

  9. Prothrombin Time (PT) and International Normalised Ratio (INR)

  10. Thrombin Clotting Time (TCT)

  11. Thrombin Generation

  12. Activated Clotting Time (ACT)

  13. Factor XII Assays

  14. Fibrinogen

  15. Platelet Counting

  16. Platelet Morphology Analysis

  17. Light Transmission Aggregometry

  18. Platelet Flow Cytometry

  19. Anti-factor Xa Assay (Anti-Xa)

  20. Reptilase Time (RT)

  21. Protamine Titration

  22. Laboratory Methods for the Assay of Tissue Factor Pathway Inhibitor (TFPI) in Human Plasma

  23. Heparin Induced Thrombocytopenia (HIT)

  24. Nijmegen-Bethesda Assay to Measure Factor VIII Inhibitors

  25. Kaolin Clotting Time

  26. The Dilute Russell Viper Venom Time (DRVVT)

  27. Platelet Neutralisation Test

  28. Antithrombin

  29. Protein C

  30. Protein S

  31. Testing for Hyperhomocysteinemia Using HPLC Technique

  32. Anticardiolipin Antibody and Anti-Beta 2 Glycoprotein I Assays

  33. Apolipoprotein (a) Phenotype Testing Using Isoelectric Focusing and Immunoblotting

  34. D-Dimer and Fibrinogen/Fibrin Degradation Products

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Tags: Paul Monagle, Haemostasis, Methods, Protocols