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From Local Invasion to Metastatic Cancer Involvement of Distant Sites Through the Lymphovascular System 1st Edition by Simone John, Christina H Stuelten, John E Niederhuber, Stanley PL Leong ISBN 1603270876 9781603270878

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From Local Invasion to Metastatic Cancer Involvement of Distant Sites Through the Lymphovascular System 1st Edition Simone John Digital Instant Download

Author(s): Simone John, Christina H. Stuelten, John E. Niederhuber (auth.), Stanley P. L. Leong (eds.)
ISBN(s): 9781603270878, 1603270876
Edition: 1
File Details: PDF, 19.40 MB
Year: 2009
Language: english
SKU: EB-11851602 Category: Tags: , , ,

From Local Invasion to Metastatic Cancer Involvement of Distant Sites Through the Lymphovascular System 1st Edition by Simone John, Christina H Stuelten, John E Niederhuber, Stanley PL Leong – Ebook PDF Instant Download/Delivery: 1603270876, 9781603270878
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ISBN 10: 1603270876 
ISBN 13: 9781603270878
Author: Simone John, Christina H Stuelten, John E Niederhuber, Stanley PL Leong

In human solid tumors, nodal status is the most important prognostic indicator for patient outcome. Recent developments in the sentinel lymph node concept have resulted in new procedures to define the first draining node as the primary gateway through which the cancer will spread. In From Local Invasion to Metastatic Cancer: Involvement of Distant Sites Through the Lymphovascular System, a panel of international authorities takes an in-depth look at the role of the lymphovascular system in the spread of cancer. The authors summarize the findings of the Second International Symposium on Cancer Metastasis: Basis for Rational Therapy summit. Specifically, the book presents important developments in the biology and clinical understanding of cancer metastasis, describes the relationship between tumor microenvironment and proliferation, and defines the process of lymphangiogenesis and angiogenesis with special reference to cancer metastasis. From Local Invasion to Metastatic Cancer: Involvement of Distant Sites Through the Lymphovascular System provides oncologists, radiologists, and cancer researchers the necessary information to study and develop new strategies to curb the process of metastasis.

From Local Invasion to Metastatic Cancer Involvement of Distant Sites Through the Lymphovascular System 1st Table of contents:

1. Innovation and Experience
1. Frontiers of Cancer Research: The Metastasis Challenge
2. Vascular Endothelial Growth Factor: Basic Biology and Clinical Applications
3. Proliferation and Cancer Metastasis from the Clinical Point of View
4. Gastrointestinal Cancer and the Lymphatic System: Patterns of Micrometastasis and Lymphatic Mapping with Clinical Outcome
5. Redefined Lymphatic Anatomy of the Breast with Clinical Implications
6. Should Axillary Lymph Node Dissection be Done for Breast Cancer?
2. Tumor Microenvironment and Proliferation
7. Overview of Tumor Cells and the Microenvironment
3. Lymphangiogenesis and Angiogenesis
8. Heme/Lymphvasculogenesis, Hem/Lymphangiogenesis, Hem/Lymphangiotumorigenesis, and Tumor Hem/Lymphangiogenesis: Need for a Terminology Adjustment
9. Tumor Lymphangiogenesis: What We Know and Don’t Know
4. Diagnostic Imaging of Cancer
10. Molecular Imaging of Cancer: Receptors, Angiogenesis, and Gene Expression
11. MRI and Ultrasound Imaging of Lymph Nodes
12. Molecular Imaging of the Sentinel Lymph Node via Lymphoseek
13. Lymphatic Disorders in Patients with Cancer
14. 3D-CT Lymphography for Mapping Metastatic Breast Sentinel Node and Axillary Nodes
15. Molecular Imaging of Neuroendocrine Cancer by Fusion SPET/CT
16. Functional Molecular Imaging of Prostate Cancer Lymph Node Metastases: Adenovirus-Mediated Lymph Node Detection
5. Therapeutic Targeting of the Lymphovascular System
17. Therapeutic Targeting of the Lymphovascular System in Cancer: Promise and Challenge
18. Comparison of Liposomal and Aqueous Blue Dye in Visualization of Lymph Nodes Prior to Lymphadenectomy
6. Molecular Mechanisms of Metastasis
19. The Role of Lymphangiogenesis in Regional Lymph Node Metastasis: Animal Models
20. Sentinel Lymph Node Chemokine Microenvironment Modulated by Melanoma Metastasis
21. Circulating and Disseminated Tumor Cells from Solid Tumors—Research and Clinical Aspects
22. Head and Neck Cancer: An Example for the Role of Chemokine Receptors in Tumor Progression and Metastasis
23. Tumor and Lymph Node Lymphangiogenesis
24. Treg, Chemokines, and Other Small Molecules: Role in Metastasis and Its Prevention
7. Molecular Targeted Therapy Against Growth Factor Receptors, Signaling Pathways and Angiogenesis as Therapeutic Targets
25. Molecular Targeting of Lymphangiogenesis and Tumor Metastasis
26. Combined Targeting of EGFR and Angiogenesis in Aerodigestive Carcinomas
27. Targeting Signaling Pathways in Cancer Therapy
8. Impact of Nodal Status and Tumor Burden in Sentinel Nodes on the Clinical Outcome
28. Micrometastasis of Melanoma to Sentinel Lymph Nodes
29. Sentinel Lymph Node Micrometastases in Breast Cancer: Prognostic Relevance and Therapeutic Implications
30. Micrometastasis of Genitourinary Cancer to Sentinel Lymph Nodes
31. Sentinel Lymph Node Mapping in Colorectal Cancer
32. Application of Cancer Biology in Cancer Staging and Predicting Clinical Outcome
9. Immune Responses in the Draining Lymph Nodes Against Cancer: Implication for Immunotherapy
33. Role of Lymph Nodes in Immunotherapy of Malignant Tumors
34. Tumor-Related Immune Modulation of the Regional Lymph Nodes
35. Reversal of Immune Suppression in Sentinel Lymph Nodes
36. Vaccine-Primed Lymph Node Cells in the Adoptive Immunotherapy of Cancer: Presence of Host Immune Suppression Induced by Established Cancer
10. The Role of Stem Cells in Cancer Metastasis
37. Cancer Stem Cells in Metastatic Melanoma
38. Implications of Cancer Stem Cells for Tumor Metastasis
39. Prostate Cancer Stem Cells and Their Involvement in Metastasis
11. Genomic Signatures of Cancer: Basis for Selective Adjuvant Therapy
40. Estrogen Receptor-Positive Breast Cancer: Traditional Prognostics, Molecular Pathology: A New Breast Cancer Taxonomy and 21st Century Personalized Prognostic and Predictive Assays
41. Molecular Signatures in Melanoma Progression
12. Promising New Treatments for Solid Tumors
42. Targeted Therapy for Breast Cancer: A Focus on HER2/neu and Antiangiogenic Therapy
43. Advances in the Treatment of Colorectal Cancer: Targeting Receptors of Disease
44. Developments in the Management of Genitourinary Malignancies: Prostate Cancer and Renal Cell Carcinoma
45. Advances in the Treatment of Lung Cancer
13. Recent Advances in the Treatment of Melanoma
46. Pegylated Interferons in the Adjuvant Treatment of Melanoma
47. Sorafenib, a Multikinase Inhibitor: Results from Clinical Trials in Melanoma Patients
48. Targeting Immunological Synapse: New Horizons in Immunotherapy for Cancer
49. Cutaneous Metastases of Melanoma: New Treatment Options
50. Neoadjuvant Approaches in Melanoma
51. Implications of Chemo/Biochemotherapy in the Treatment of Metastatic Melanoma
14. Future Perspectives
52. Future Perspectives for Cancer Metastasis: Unanswered Questions and Unquestioned Answers

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Tags: Simone John, Christina H Stuelten, John E Niederhuber, Stanley PL Leong, Local Invasion, Metastatic Cancer, Lymphovascular System