Early Diagnosis and Treatment of Cancer Series Ovarian Cancer Expert Consult 1st Edition by Robert Bristow, Deborah Armstrong – Ebook PDF Instant Download/Delivery: 1416046852, 9781416046851
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ISBN 10: 1416046852
ISBN 13: 9781416046851
Author: Robert Bristow, Deborah Armstrong
Early Diagnosis and Treatment of Cancer Series Ovarian Cancer Expert Consult 1st Table of contents:
Chapter 1: Epidemiology and Clinical Presentation of Ovarian Cancer
Introduction
Epidemiology
Risk Factors
Clinical Presentation
Prognostic Factors
Residual Disease after Cytoreductive Surgery
Tumor Biology
Chapter 2: Biology and Pathology of Ovarian Cancer
Introduction
Clinical and Pathologic Observations Supporting the Dualistic Ovarian Carcinogenesis Model
A Proposed Model of Ovarian Carcinogenesis
Molecular Evidence Supporting the Ovarian Carcinogenesis Model
Molecular Alterations in Other Nonserous Types of Ovarian Carcinomas
Future Study of Kinase Inhibitors in Treating Ovarian Cancer
Chapter 3: Ovarian Cancer Family Syndromes and Genetic Testing
Introduction
Genetics Review
Hereditary Ovarian Cancer Syndromes
Genetic Assessment
Conclusion
Chapter 4: Ovarian Cancer Prevention: Chemoprevention and Prophylactic Surgery
Introduction
Epidemiology
Ovarian Cancer Prevention
Genetic Predisposition
Mechanisms of Action
Ovarian Cancer Chemoprevention in the General Population
Chemoprevention for Women with Increased Risk
Prophylactic Surgery in the General Population
Prophylactic Surgery in the High-Risk Population
Conclusions
Chapter 5: Imaging of Ovarian Cancer
Overview of the Roles of Imaging in Ovarian Cancer
Screening for Ovarian Cancer
Detection and Characterization of Ovarian Tumors
Staging
Follow-up
Conclusion
Chapter 6: Ovarian Cancer Screening
Introduction
Principles of Cancer Screening
Challenges of Ovarian Cancer Screening
General Population Screening
Ovarian Cancer Screening in High-Risk Women
Conclusion
Chapter 7: Ovarian Cancer Surgery
Introduction
Advanced-Stage Epithelial Ovarian Cancer
Early-Stage Epithelial Ovarian Cancer
Risk-Reducing Surgery
Ovarian Tumors of Low Malignant Potential
Malignant Germ Cell Tumors of the Ovary
Sex Cord-Stromal Tumors of the Ovary
Chapter 8: Chemotherapy for Ovarian Cancer
EARLY OVARIAN CARCINOMA
Definition of Early Ovarian Cancer
Natural History of Untreated Early Ovarian Carcinoma
Importance of Surgical Staging
Does Adjuvant Chemotherapy Improve Outcome?
Choice of Chemotherapy and Duration of Treatment
Future Directions
Summary
ADVANCED OVARIAN CARCINOMA (STAGES III AND IV)
Evolution of Platinum and Taxane Agents
Equivalency of Carboplatin and Cisplatin
Taxanes
New Combinations and Dose Schedules
Intraperitoneal Chemotherapy
Maintenance Therapy
Neoadjuvant Therapy
Chapter 9: Management of Recurrent Ovarian Cancer: Chemotherapy and Clinical Trials
Background
Definition of Recurrent versus Platinum-Resistant Ovarian Cancer
Goals of Second-Line Chemotherapy in Ovarian Cancer
Chemotherapy of Recurrent (Potentially Platinum-Sensitive) Ovarian Cancer
Treatment of Platinum-Resistant Ovarian Cancer
Chemoresistance and Chemosensitivity Testing in the Selection of Second-Line Anti-Neoplastic Drug Delivery
Ongoing Research in Recurrent and Resistant Ovarian Cancer
Chapter 10: Secondary Cytoreduction in the Treatment of Recurrent Ovarian Cancer
Introduction
Clinical and Theoretical Background of Surgical Cytoreduction
Secondary Cytoreduction
Patient Selection
Preoperative Evaluation and Imaging
Procedures, Complications, and Outcome of Secondary Cytoreductive Surgery
Hyperthermic Intraperitoneal Chemotherapy
Conclusions and Guidelines
Chapter 11: Borderline Epithelial Ovarian Tumors, Sex Cord-Stromal Tumors, and Germ Cell Tumors
Borderline Ovarian Tumors
Sex Cord-Stromal Tumors
Germ Cell Tumors
Chapter 12: Conclusion
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