Cosmeceuticals and Active Cosmetics 3rd Edition by Raja Sivamani, Jared Jagdeo, Peter Elsner, Howard Maibach ISBN 1482214164 9781482214161
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ISBN 10: 1482214164
ISBN 13: 978-1482214161
Author: Raja Sivamani, Jared R. Jagdeo, Peter Elsner, Howard I. Maibach
Cosmeceuticals and Active Cosmetics discusses the science of nearly two dozen cosmeceuticals used today. This third edition provides ample evidence on specific cosmeceutical substances, their classes of use, skin conditions for which they are used, and points of interest arising from other considerations, such as toxicology and manufacturing. The book discusses both cosmetic and therapeutic uses of cosmeceuticals for various conditions including rosacea, dry skin, alopecia, eczema, seborrheic dermatitis, purpura, and vitiligo.
Active ingredients in the following products are discussed: caffeine, curcumin, green tea, Rhodiola rosea, milk thistle, and more. Also covered are topical peptides and proteins, amino acids and derivatives, antioxidants, vitamins E and C, niacinamide, botanical extracts, and biomarine actives. Providing ample scientific references, this book is an excellent guide to understanding the science behind the use of cosmeceuticals to treat a variety of dermatological conditions.
Cosmeceuticals and Active Cosmetics 3rd Table of contents:
Chapter 1 – Bakuchiol: A Retinol-Like Functional Compound, Modulating Multiple Retinol and Non-Retinol Targets
Background
- Bakuchiol, a Functional Analog of Retinol
- Preventative and Restorative Anti-Aging
Mechanisms and Benefits
- Antioxidant
- Anti-Inflammatory Properties
- Matrix Metalloprotease (MMP) Regulation
- Extracellular Matrix Proteins
- Skin Hydration and Barrier Homeostasis
- Anti-Acne
- Skin Lightening and Even Toning
Other Targets
- Protein Tyrosine Phosphatases (PTPs)
- DNA Polymerases
- Tumor Suppressor p53
- STAT3 and HIF-1
Conclusion and References
Chapter 2 – Cutaneous Applications of Caffeine
Introduction and Background
- Clinical Uses
- Skin Barrier Penetration
Benefits
- Non-Melanoma Skin Cancer Prevention
- Antioxidant Properties
- Facial Redness Reduction
- Anti-Cellulite
- Hair Growth
Future Applications and Conclusion
Chapter 3 – Curcumin in Cosmetics: Biochemical Basis for Skin Repair with Use of Topical Curcumin
Introduction
- Skin Injury and Signaling Pathways
- Role of NF-κB: Inhibition by Curcumin
Applications
- Burns and UV Damage Repair
- DNA Protection
- Clinical Uses for Photodamaged Skin
Summary and References
Chapter 4 – The Cosmetic and Therapeutic Uses for EGCG
Overview and Cosmetic Applications
- Anti-Aging and Sunscreen
- Hair Growth
Skin Diseases
- Keloids
- Psoriasis and Acne
Toxicity, Pharmacokinetics, and Conclusion
Chapter 5 – Ellagic Acid
Overview
- UV-Induced Skin Aging
- Hyperpigmentation
Conclusion
Chapter 6 – Gamma-Linolenic Acid–Containing Vegetable Oils
Introduction and Mechanisms
- Clinical Studies: Atopic Eczema and Dry Skin
- Sources and Effects on Skin Health
Conclusions
Chapter 7 – Hexylresorcinol: Providing Skin Benefits by Modulating Multiple Molecular Targets
Mechanisms
- Anti-Aging
- Antioxidant and Anti-Inflammatory Effects
- Skin Lightening
Clinical Studies and Formulations
Chapter 8 – Hydroxyacids
Introduction
- Chemical Structure and Natural Sources
- Effects on Skin Physiology
Clinical Uses and Safety
Chapter 9 – Kinetin
Introduction
- Chemistry and Biology
- Mechanism of Action
Clinical Studies
Chapter 10 – Topical Resveratrol
Introduction and Cosmeceutical Uses
- Antioxidant and Photoprotective Properties
- Skin Barrier Repair
Other Applications and Conclusion
Chapter 11 – Impact of Rhodiola rosea on Skin
Phytochemistry and Benefits
- Anti-Aging Properties
Potential Skin Applications
Chapter 12 – Silymarin
Introduction
- Antioxidant and Photoprotective Properties
- Anti-Fibrotic Effects
Conclusion
Chapter 13 – Topical Niacinamide
Introduction and Background
- Medical and Cosmeceutical Uses
- Inflammatory Dermatoses and Acne
Commercial Applications
Chapter 14 – Anti-Aging Topical Peptides and Proteins
Types of Peptides
- Signal Peptides (GHK-Cu, SAP, etc.)
- Neurotransmitter Inhibitor Peptides
Proteins and Growth Factors
Chapter 15 – Amino Acids and Derivatives
Skin Functions and Delivery Systems
Chapter 16 – Antioxidants
Introduction
- Environmental Stressors and Skin Aging
- Common Antioxidants: Vitamins E, C, and Polyphenols
Evaluations and Sunscreen Applications
Chapter 17 – Decorative Cosmetics
Introduction
- Pigment Chemistry
- Formulations and Quality Assurance
Chapter 18 – Hair Cosmetics and Cosmeceuticals
Introduction
- Shampoos, Conditioners, and Natural Products
Chapter 19 – Moisturizers: Treatment of Dry Skin Syndrome and Barrier Defects
Composition and Applications
Chapter 20 – Cosmeceutical Treatments of the Nail
Anatomy and Treatments
Chapter 21 – Botanicals and Cosmeceuticals for Sun Protection
Photoprotective Botanicals
Chapter 22 – UV Care
Skin Damage and Prevention
Chapter 23 – Topical Vitamins E, C, and Ferulic Acid and L-Selenomethionine
Chapter 24 – The Use of Cosmeceuticals in Rosacea
Chapter 25 – Cosmeceutical Treatments for Androgenetic Alopecia
Chapter 26 – Eczema, Xerosis, and Cutaneous Barrier Repair
Chapter 27 – Melasma and Depigmentation Agents
Chapter 28 – Oily Skin, Seborrhea, and Seborrheic Dermatitis
Chapter 29 – Cosmeceutical Treatments for Purpura
Chapter 30 – Vitiligo (Repigmentation Agents)
Chapter 31 – Botanical Extracts
Chapter 32 – Biomarine Actives
Chapter 33 – Analytical Chemistry of Botanical Extracts
Chapter 34 – Legal Distinction in the United States between a Cosmetic and a Drug
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Raja Sivamani,Jared Jagdeo,Peter Elsner,Howard Maibach,Cosmeceuticals,Ative Cosmetics 3rd