Cancer Cell Signaling Methods and Protocols 2nd Edition by Martha Robles Flores ISBN 1493908553 9781493908554

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Product details:
ISBN 10: 1493908553
ISBN 13: 9781493908554
Author: Martha Robles Flores

Cancer Cell Signaling: Methods and Protocols, Second Edition brings together the most recent advances in cancer cell signaling knowledge along with recent progress in the development of novel strategies and experimental cell models to study human cancer. Opening with a section on targeting cancer cell metabolism as an anticancer strategy, this detailed volume continues with parts describing protocols to study epigenetic control of cancer, protocols to study cancer metastasis, as well as two new techniques for cancer study. Written for the highly successful Methods in Molecular Biology series, chapters include introductions for their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls.

Authoritative and timely, Cancer Cell Signaling: Methods and Protocols, Second Edition is an ideal guide to the techniques that will aid researchers in exploiting our current knowledge in order to make a profound impact in cancer prevention and treatment.

Cancer Cell Signaling Methods and Protocols 2nd Edition Table of contents:

• Part One: Targeting Cancer Cell Metabolism

  • Chapter 1: Use of Biguanides to Improve Response to Chemotherapy

  • Chapter 2: Evaluating Response to Metformin/Cisplatin Combination in Cancer Cells via Metabolic Measurement and Clonogenic Survival

  • Chapter 3: Quantifying the Autophagy-Triggering Effects of Drugs in Cell Spheroids with Live Fluorescence Microscopy

• Part Two: Epigenetic Control of Cancer

  • Chapter 4: Interdependency Between Genetic and Epigenetic Regulatory Defects in Cancer

  • Chapter 5: Experimental Strategies to Manipulate the Cellular Levels of the Multifunctional Factor CTCF

• Part Three: Cancer Metastasis

  • Chapter 6: Prostate Cancer Spheroids: A Three-Dimensional Model for Studying Tumor Heterogeneity

  • Chapter 7: Enrichment and Transcriptional Characterization of Stem Cells Isolated from Human Glioblastoma Cell Lines

• Part Four: New Technologies in Cancer Study

  • Chapter 8: Reverse Docking for the Identification of Molecular Targets of Anticancer Compounds

  • Chapter 9: Mouse Model for Efficient Simultaneous Targeting of Glycolysis, Glutaminolysis, and De Novo Synthesis of Fatty Acids in Colon Cancer

• Conclusion

  • Summary of Key Insights

  • Future Directions for Cancer Cell Signaling Research

• Appendices

  • Glossary of Terms

  • Additional Resources

• References

  • Comprehensive Bibliography

• Index

  • Detailed Index of Topics and Terms

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Martha Robles Flores,Cancer Cell,Signaling Methods,Protocols