Biotechnology and Biopharmaceuticals Transforming Proteins and Genes into Drugs 1st Edition – Ebook PDF Instant Download/Delivery:0471206903 ,978-0471206903
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Product details:
ISBN 10: 0471206903
ISBN 13: 978-0471206903
Author: Rodney J Y Ho,Milo Gibaldi
Biotechnology and Biopharmaceuticals: Transforming Proteins and Genes into Drugs defines biotechnology from the perspective of pharmaceuticals. The first section focuses on the process of transforming a biologic macromolecule into a therapeutic agent, while the second section provides a brief overview of each class of macromolecule with respect to physiological role and clinical application. Additional detail is also provided in the second section for each FDA approved, recombinantly derived biopharmaceutical for each category of macromolecule. The final section looks to the future and the new advances that will enhance our ability to develop new macromolecules into effective biopharmaceuticals. This last section discusses various drug delivery strategies while also describing gene and cell therapy strategies.
Table of contents:
Part 1: Overview and Drug Development
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Ch.1: Introduction to Biopharmaceuticals (1-9)
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Ch.2: Comparative Development of Proteins/Genes vs. Small Molecules (11-20)
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Ch.3: Biotechnology Industry Perspective (21-34)
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Ch.4: Technologies and Processes in Drug Development (35-95)
Part 2: Pharmacology and Clinical Applications
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Ch.5: Pharmacology, Toxicology, Dosage Forms, and Clinical Response (97-123)
Part 3: Key Product Categories
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Ch.6: Hematopoietic Growth and Coagulation Factors (125-159)
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Ch.7: Interferons and Cytokines for Infectious Diseases and Cancer (161-208)
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Ch.8: Hormones (209-243)
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Ch.9: Enzymes (245-269)
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Ch.10: Antibodies and Derivatives (271-311)
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Ch.11: Vaccines (313-329)
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Ch.12: Other Products: Monographs (331-335)
Part 4: Advanced Technologies and Personalized Medicine
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Ch.13: Advanced Drug Delivery (337-380)
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Ch.14: Individualized Drug Regimens: Pharmacokinetics and Pharmacogenetics (381-400)
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Ch.15: Gene and Cell Therapy (401-426)
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Ch.16: Integrating Discovery and Development: Genomics and Proteomics (427-444)
Part 5: Appendices and Index
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App I: Dosage Forms, Pharmacokinetics, and Disposition Data (445-466)
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App II: Molecular Characteristics and Therapeutic Uses (467-493)
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App III: Nomenclature of Biotechnology Products (495-498)
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App IV: Trade, Common, and Scientific Names (499-525)
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App V: Additional Information Tables (527-538)
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Index: (539-556)
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Tags: Rodney J Y Ho, Milo Gibaldi, Biotechnology, Biopharmaceuticals Transforming, Drugs 1st


