Biomedical Nanotechnology 1st Edition by Neelina H Malsch – Ebook PDF Instant Download/Delivery: 1420028626, 9781420028621
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ISBN 10: 1420028626
ISBN 13: 9781420028621
Author: Neelina H Malsch
Biomedical Nanotechnology 1st Table of contents:
Chapter 1: Trends in Biomedical Nanotechnology Programs Worldwide
I. Introduction
II. Biomedical Nanotechnology In The United States
A. National Nanotechnology Initiative
B. Federal Agencies
1. National Science Foundation
a. Nanobiotechnology Center at Cornell University
b. National Nanofabrication Users Network
c. Columbia University
d. Northwestern University
e. Rensselaer Polytechnic University
f. Rice University
2. Department of Defense
a. Institute for Soldier Nanotechnologies
3. National Aeronautics and Space Administration
4. National Institutes of Health
5. Environmental Protection Agency
III. Biomedical Nanotechnology In Europe
A. Introduction
B. Biomedical Nanotechnology in the EU Research Program
C. France
1. Government Policies and Initiatives
2. Networks
D. Germany
1. Strategy
2. Nanobiotechnology
3. Competence Networks
4. Research Centers
a. CAESAR
b. Charité
c. Institute for New Materials
d. Institute of Microtechnology Mainz
e. Max Planck Institute of Colloids and Interfaces
E. United Kingdom
1. Introduction
2. Interdisciplinary Research Collaborations
IV. JAPAN
A. Introduction
B. Government Policies and Initiatives
C. Support and Development
D. Nanotechnology Virtual Laboratory
E. Nanotechnology Project of Ministry of Health, Labor, and Welfare
V. Conclusion
Chapter 2: Nanotechnology and Trends in Drug Delivery Systems with Self-Assembled Carriers
I. Introduction
II. Drug Delivery Systems Since The 1980s
A. Government Funding for Nanodrug Delivery Systems
III. Chemical System Engineering And Nanotechnology
IV. Toward Development Of Drug Delivery Systems With Bionanotechnology
A. Self-Assembly and Self-Organization
B. Nanoparticles and Nano-Sized Spaces
C. Quantum Dot (Semiconductor Nanoparticle)
V. Safety Of The Human Body And The Environment
VI. Conclusion
References
Chapter 3: Implants and Prostheses
I. Introduction
II. Biomaterials
A. Introduction
B. Properties of Biomaterials
1. Bulk Properties
2. Surface Properties
C. Biomaterials Science: A Multidisciplinary Field
III. Biological Processes
A. Wound Healing Processes
1. Thrombus Formation
2. Inflammatory Phase
3. Reparative Phase
4. Tissue Remodeling
B. Macrophages
C. Biomaterial Interface Processes
D. Foreign Body Reaction
IV. Nanotechnology In Implantology
A. Introduction
B. Current Nanofabrication Methods
1. Lithography
2. Colloidal Resists
3. Self-Assembly Systems
4. Soft Lithography
5. Biomimetic Approaches
6. DNA Coatings
C. Influence of Biomaterials with Nanostructures on Cell Behavior
1. Topographical Nanostructures
2. Protein and Peptide Nanostructures
3. Calcium Phosphate Nanostructures
V. CONSIDERATIONS
A. Topographical versus Chemical Cues
B. Natural versus Synthetic Nanostructures
VI. Conclusions
References
Chapter 4: Diagnostics and High Throughput Screening
I. High Throughput Screening And Nanotechnology Tools For Biomedicine
A. Definition of High Throughput Screening
B. HTPS Architectures
C. Nanotechnology and HTPS
D. Principal Applications of HTPS in Biomedicine
II. Flat Surface Microarrays
A. Dna Microarrays
B. Protein Arrays
C. Affinity Capture Arrays
D. Carbohydrate Arrays
E. Cell Arrays
F. Tissue Microarrays
III. Nonpositional Htps Platforms
A. Automated Ligand Identification System
B. Fiberoptic Arrays
C. Suspension Arrays
IV. Microfluidics, Microelectromechanical Systems, And Micro Total Analysis Systems
V. New Trends In Detection Systems
A. New Labeling Systems: Nanoparticles and Quantum Dots
B. Label-Free Detection Systems
VI. Bioinformatics
VII. Applications Of Htps In Biomedicine
A. Genetic Diseases
B. Cancer
C. Genetic Epidemiology
D. Tissue Typing
E. Infectious Diseases
F. Therapeutics: Drug Discovery and Validation
VIII. Future Of Nanotechnology And Htps
References
Chapter 5: Nano-Enabled Components and Systems for Biodefense
I. Introduction
II. Sensor Component Of Nano-Enabled Biodefense
A. Importance of Information in Biodefense and Sensor Characteristics
III. Nano-Enabled Sensors For Monitoring Exposures
A. Nano-Enabled Sensors for Monitoring Airborne Exposures
1. Biosensors
2. Electronic Nose
B. Nano-Enabled Sensors for Monitoring Contact Exposures
1. Microcantilevers for Biosensing
2. Nanoparticles and Nanocrystals
3. Functionalized Nanotubes and Nanowires
IV. Nanoscale Components Of Sensing Systems
A. Nanolithography of Biological Molecules and Sensing Materials
B. Nanoparticle Arrays on Surfaces
C. Functional Three-Dimensional Nanostructures
D. Molecular Imprinting: Construction of Recognition Elements at Nanoscale
V. Modifications Of Natural Systems On The Nanoscale For Sensing
A. Phage Display
B. Whole-Cell Sensing Systems
VI. Nanomaterials As Enablers For Biodefense
A. Fibers, Fabrics, Membranes, and Textiles
B. Conducting Polymers
C. Nanoscale Decontaminants
VII. Integration And Multifunctional System Concepts
A. Integrated Technology Examples
VIII. Perspectives
A. Potential of Nanotechnology
B. Limitations and Challenges
C. Conclusions
References
Chapter 6: Social and Economic Contexts: Making Choices in the Development of Biomedical Nanotechnology
I. Introduction
II. Global Trends In Health Care Needs
A. Social and Economic Damages Arising from Disease
B. Diseases
1. Infectious Diseases
a. Types of Infectious Diseases and Treatments
2. Cancer
3. Cardiovascular Diseases
4. Other Diseases
C. Disabilities
1. Blindness and Visual Impairments
a. Artificial Eyes
b. Paralysis and Prostheses
D. Discussion
III. Health Care Systems: Trends And Economics
A. Health Care Market
B. Characteristics of Health Care Systems
C. Discussion
D. Markets for Biomedical Nanotechnology R&D
1. Pharmaceutical R&D
a. Patents
b. Global Competition
E. Orphan Drugs and Tropical Diseases
1. Discussion
2. Medical Device R&D
IV. Societal Benefits And Ethical, Legal, And Social Aspects Of New Technology
A. Views of Nanotechnology Experts on Socioeconomic Aspects of Their Work
1. Methods of Coping with Ethical, Legal, and Social Aspects
2. Researchers’ Opinions about Societal Aspects of Their Research
a. Nanodrug Delivery
b. Diagnostics and Drug Discovery
3. Discussion
B. Main Issues
1. Opportunities
2. Challenges
3. Beneficiaries and Patients
V. Addressing Ethical, Legal, And Social Concerns
A. Regulation
B. Health Technology Assessment
1. Need for New Legislation
C. Participatory Technology Assessment
D. Technology Forcing
VI. Conclusions
References
Chapter 7: Potential Risks and Remedies
I. Introduction
II. Nanomaterials In The Human Body
A. Implants
B. Bone Regeneration
C. Diagnosis and Treatment of Diseases
D. Cosmetics
III. Toxicities Of Nanomaterials
A. Nanoparticles
B. Fullerenes
C. Carbon Nanotubes
IV. Stakeholders’ Positions On Safety And Regulation Of Nanomaterials
A. Scientific Community
B. Industry
C. Citizen Interest Groups
D. The Public
E. Government Funding and Regulatory Agencies
1. U.S. Government Initiatives
2. Government Initiatives in Europe
V. Potential Paths For Regulation
A. Regulation through the Market
B. Application of Current Regulations
C. Regulation through Accident
D. Regulatory Capture
E. Self-Regulation
F. Ban
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