Biomedical Hydrogels Biochemistry Manufacture and Medical Applications Woodhead Publishing in Materials 1st Edition by S Rimmer ISBN 1845695909 9781845695903
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ISBN 10: 1845695909
ISBN 13: 9781845695903
Author: S Rimmer
Part one of this book concentrates on the processing of hydrogels, covering hydrogel swelling behaviour, superabsorbent cellulose-based hydrogels and regulation of novel hydrogel products, as well as chapters focusing on the structure and properties of hydrogels and different fabrication technologies. Part two covers existing and novel applications of hydrogels, including chapters on spinal disc and cartilage replacement implants, hydrogels for ophthalmic prostheses and hydrogels for wound healing applications. The role of hydrogels in imaging implants in situ is also discussed.
With its distinguished editor and international team of contributors, Biomedical hydrogels is an excellent reference for biomedical research scientists and engineers in industry and academia, as well as others involved in research in this area, such as research clinicians.
- Examines the diverse range and use of hydrogels, focusing on processing methods and novel applications
- Comprehensive book explores the structure and properties of hydrogels and different fabrication technologies
- Covers important areas such as processing of hydrogels, covering hydrogel swelling behaviour, superabsorbent cellulose-based hydrogels and regulation of novel hydrogel products
Biomedical Hydrogels Biochemistry Manufacture and Medical Applications Woodhead Publishing in Materials 1st Table of contents:
Part I: Processing of Hydrogels
1. Hydrogel swelling behavior and its biomedical applications
1.1 Basics of hydrogels
1.2 Swelling of hydrogels: water diffusion into hydrogels
1.3 Stimulus-responsive hydrogels
1.4 Examples of environment-sensitive hydrogels
1.5 Future trends
1.6 References
2. Superabsorbent cellulose-based hydrogels for biomedical applications
2.1 Introduction
2.2 Cellulose-based hydrogels and crosslinking strategies
2.3 Hydrogel properties and thermodynamics
2.4 Applications
2.5 Conclusions
2.6 References
3. Synthesis of hydrogels for biomedical applications: control of structure and properties
3.1 Introduction
3.2 Cross-linking of high molecular weight polymers
3.3 Copolymerization with multi-functional monomers
3.4 Multiphase hydrogels
3.5 Functional hydrogels
3.6 Conclusion
3.7 References
4. Processing and fabrication technologies for biomedical hydrogels
4.1 Introduction
4.2 Applications
4.3 Gelation
4.4 Physical crosslinking
4.5 Photopolymerization and photopatterning
4.6 Stereolithography
4.7 Two-photon laser scanning photolithography
4.8 Processing of multicomponent hydrogels
4.9 Future trends
4.10 Acknowledgements
4.11 References
5. Regulation of novel biomedical hydrogel products
5.1 Introduction
5.2 Regulatory jurisdictions
5.3 Regulatory frameworks
5.4 Risk-based device classification
5.5 Non-clinical testing
5.6 Clinical data and studies
5.7 Marketing authorization processes
5.8 Quality system requirements
5.9 Post-market requirements
5.10 Future trends
5.11 Sources of further information and advice
Part II: Applications of Hydrogels
6. Spinal disc implants using hydrogels
6.1 Introduction
6.2 Intervertebral disc
6.3 Disc implant
6.4 Conclusion
6.5 References
7. Hydrogels for intraocular lenses and other ophthalmic prostheses
7.1 Introduction
7.2 Intraocular lenses
7.3 Vitreous substitutes
7.4 Tissue adhesives
7.5 Conclusions
7.6 Acknowledgements
7.7 References
8. Cartilage replacement implants using hydrogels
8.1 Introduction
8.2 Historical background in cartilage repair and injury: existing therapies
8.3 First and second generation tissue engineering
8.4 Third generation tissue engineering
8.5 Future trends
8.6 References
9. Hydrogels for wound healing applications
9.1 Introduction
9.2 Requirements of an ideal wound care system
9.3 Hydrogels for wound healing applications
9.4 Natural hydrogels for wound healing applications
9.5 Synthetic and other hydrogels for wound healing applications
9.6 Commercial dressings
9.7 Future trends
9.8 Conclusion
9.9 References
9.10 Appendix: list of abbreviations
10. Imaging hydrogel implants in situ
10.1 Introduction
10.2 Rationale for imaging implants in situ
10.3 Imaging modalities and their advantages and disadvantages for the in situ imaging of hydrogel implants
10.4 Challenges of imaging in situ
10.5 Contrast enhancement
10.6 Characterization of implants (in vitro and in vivo)
10.7 Characterization of in vivo healing
10.8 Conclusions
10.9 Sources of further information and advice
10.10 References
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