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Advances in Immunology Volume 89 1st Edition by Frederick Alt ISBN 0120224909 9780120224906

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Advances in Immunology 89 1st Edition Frederick W. Alt Digital Instant Download

Author(s): Frederick W. Alt, K. Frank Austen, Tasuku Honjo, Fritz Melchers, Jonathan W. Uhr and Emil R. Unanue (Eds.)
ISBN(s): 9780120224906, 0120224909
Edition: 1
File Details: PDF, 4.71 MB
Year: 2006
Language: english
SKU: EB-1887418 Category: Tags: , , , ,

Advances in Immunology Volume 89 1st Edition by Frederick Alt – Ebook PDF Instant Download/Delivery: 0120224909 ,9780120224906
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Product details:
ISBN 10: 0120224909
ISBN 13: 9780120224906
Author: Frederick Alt

Advances in Immunology, a long established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for future research.

Advances in Immunology Volume 89 1st Edition Table of contents:

Part I: Molecular Mechanisms in Immunity

Chapter 1: Genetic Regulation of Immune Responses

  • Mechanisms of Immunoglobulin Gene Rearrangement
  • Epigenetic Regulation in Immunity
  • Advances in Understanding V(D)J Recombination

Chapter 2: The Role of Transcription Factors in Immunological Development

  • Key Transcription Factors in T-Cell and B-Cell Development
  • The Regulation of Immune Cell Differentiation
  • Transcriptional Networks in Immune System Homeostasis

Chapter 3: Signal Transduction in Immune Cells

  • Immune Receptor Signaling Pathways
  • Kinases and Phosphatases in Immunity
  • Crosstalk Between Immunoreceptors and Cytokine Signaling

Part II: Adaptive Immunity

Chapter 4: T Cell Immunology: From Development to Activation

  • Thymic Development and Selection of T Cells
  • T-Cell Receptor Signaling
  • Regulation of T-Cell Responses and Memory Formation

Chapter 5: B Cell Immunology and Antibody Production

  • B-Cell Development and Antibody Production
  • Class Switching and Somatic Hypermutation
  • The Role of B Cells in Autoimmunity and Immune Surveillance

Chapter 6: Regulatory Mechanisms in Adaptive Immunity

  • T-Cell and B-Cell Tolerance Mechanisms
  • Regulatory T Cells in Immune Homeostasis
  • Immunological Memory and its Regulation

Part III: Innate Immunity

Chapter 7: Pattern Recognition Receptors and Innate Immunity

  • The Role of PRRs in Detecting Pathogens
  • Innate Immune Response to Infection
  • Toll-Like Receptors and Their Signaling Pathways

Chapter 8: Innate Immune Cells in Health and Disease

  • Macrophages, Dendritic Cells, and Neutrophils in Immunity
  • The Role of Natural Killer (NK) Cells
  • Innate Lymphoid Cells and Their Functions

Chapter 9: Inflammation and Its Regulation

  • Mechanisms of Inflammation in Immune Responses
  • Chronic Inflammation and Disease
  • Anti-inflammatory Pathways and Therapeutic Interventions

Part IV: Immunopathology

Chapter 10: Immunological Mechanisms in Autoimmunity

  • Genetic and Environmental Factors in Autoimmune Diseases
  • Molecular Mechanisms of Autoimmunity
  • Therapeutic Approaches for Autoimmune Diseases

Chapter 11: Cancer Immunology

  • The Immune System and Tumor Surveillance
  • Tumor Escape Mechanisms
  • Immunotherapy in Cancer Treatment

Chapter 12: Immunodeficiency Diseases

  • Primary and Secondary Immunodeficiencies
  • Advances in Gene Therapy for Immunodeficiencies
  • Diagnostic Approaches for Immunodeficiencies

Part V: Immunological Technologies and Applications

Chapter 13: Advances in Immunodiagnostics

  • New Technologies in Immune System Monitoring
  • Biomarkers for Immune Responses
  • Flow Cytometry, ELISA, and Mass Cytometry

Chapter 14: Immunotherapies and Vaccines

  • Immune Checkpoint Inhibitors and Cancer Vaccines
  • Advances in Vaccine Development for Infectious Diseases
  • Cell-Based Immunotherapies

Chapter 15: Emerging Topics in Immunology

  • Immunology of Aging
  • The Microbiome and Its Effect on Immunity
  • Advances in Personalized Immunology and Precision Medicine

Conclusion

  • Summary of Key Advances in Immunology
  • The Future of Immunology Research
  • Emerging Challenges and Opportunities in the Field

Bibliography

Index

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