Phytochemistry of Plants of Genus Cassia 1st Edition by Brijesh Kumar, Vikas Bajpai, Vikaskumar Gond, Subhashis Pal, Naibedya Chattopadhyayay ISBN 1032030216 9781032030210

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ISBN 10: 1032030216
ISBN 13:  9781032030210
Author: Brijesh Kumar, Vikas Bajpai, Vikaskumar Gond, Subhashis Pal, Naibedya Chattopadhyayay

Cassia is an indigenous plant in Africa, Latin America, Northern Australia and Southeast Asia. Several Cassia species are of high commercial and medicinal significance since they are used as spices and in traditional medicines. Currently plants from genus Cassia is in great demand due to their immense medicinal properties. Cassia species have various pharmacological activities such as antibacterial, analgesic, antiinflammatory, antiarthritic, hepatoprotective, antitumor, antifertility, antifungal, antioxidant, antileishmaniatic, antimicrobial, CNS and hypoglycaemic activitiy. Different class of compounds reported from Cassia species are anthraquinones, phenolics, flavonoids, chromenes, terpenes, proanthocyanidins, coumarins, chromones and lignans. The taxonomy and nomenclature of Cassia species are quite complex. It is very difficult to differentiate them due to their overlapping morphological characters and close similarities. This usually leads to misidentification and misinterpretation of the components.

Phytochemistry of Plants of Genus Cassia 1st Table of contents:

1 Introduction
1.1 Geographical Distribution of Genus Cassia
1.2 Phytography of Genus Cassia
1.3 Phytochemistry of Genus Cassia
1.3.1 Leaves
1.3.2 Root
1.3.3 Stem Bark
1.3.4 Seed
1.4 Pharmacological Activities of Genus Cassia
1.5 Traditional Uses of Genus Cassia
1.6 Introduction of Selected Cassia Species
1.6.1 Cassia Auriculata
1.6.1.1 Botany
1.6.1.2 Medicinal Property
1.6.1.3 Phytochemistry
1.6.2 Cassia Fistula
1.6.2.1 Botany
1.6.2.2 Medicinal Property
1.6.2.3 Phytochemistry
1.6.3 Cassia Occidentalis
1.6.3.1 Botany
1.6.3.2 Medicinal Property
1.6.3.3 Phytochemistry
1.6.4 Cassia Siamea
1.6.4.1 Botany
1.6.4.2 Medicinal Property
1.6.4.3 Phytochemistry
2 Qualitative and Quantitative Determination of Bioactive Phytochemicals in Selected Cassia Species Using HPLC-ESI-QTOF-MS and UPLC-ESI-QqQLIT-MS/MS
2.1 Plant Material and Chemicals
2.2 Extraction and Sample Preparation
2.3 Preparation of Standard Solution
2.4 HPLC-ESI-QTOF-MS Conditions
2.4.1 Instrumentation
2.4.2 HPLC Condition
2.4.3 Mass Spectrometric Conditions
2.5 UPLC- ESI-QqQLIT-MS/MS Conditions
2.5.1 Instrumental Parameters
2.5.2 UPLC Condition
2.5.3 Mass Spectrometric Conditions
2.5.4 Source Parameters Optimized for Negative Mode
2.5.5 Compound-Dependent Parameters
2.6 Principal Component Analysis
2.7 Optimization of UPLC conditions
2.8 Optimization of MS/MS Conditions
2.9 Analytical Method Validation
2.9.1 Linearity, LOD and LOQ
2.9.2 Precision, Stability and Recovery
2.10 Qualitative Analysis of Cassia Occidentalis Samples
2.11 Quantitative Analysis of Cassia Species Samples
2.12 Principal Component Analysis to Study Chemical Variations
3 In-vitro Anti-Proliferative Screening in Selected Cassia Species
3.1 Plant Material
3.2 Extraction and Sample Preparation
3.3 Cell Lines and Anti-Proliferative Assay
3.4 In-vitro Anti-Proliferative Activity Evaluation
4 Bone Regeneration Effect of Cassia occidentalis Linn. Extract and Its Isolated Compounds
4.1 Bone Healing Property of Cassia occidentalis
4.2 Osteoporosis and Arthritis
4.3 The Effects of CO Extract Fraction and Formulation
4.4 Effects of Compounds Derived from CO Extract
4.4.1 Apigenin
4.4.2 Emodin
4.4.3 Luteolin
4.4.4 Caryophyllene
4.4.5 Kaempferol
4.4.6 Quercetin
5 Conclusions

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Brijesh Kumar,Vikas Bajpai,Vikaskumar Gond,Subhashis Pal,Naibedya Chattopadhyayay,Phytochemistry,Genus Cassia