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Regenerative Medicine for Peripheral Artery Disease 1st Edition by Emile R Mohler, Brian Annex ISBN 0128013443 9780128013441

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Regenerative Medicine for Peripheral Artery Disease 1st Edition Emile R Mohler Digital Instant Download

Author(s): Emile R Mohler, Brian Annex
ISBN(s): 9780128013441, 0128013443
Edition: 1
File Details: PDF, 5.30 MB
Year: 2016
Language: english
SKU: EB-5601332 Category: Tags: ,

Regenerative Medicine for Peripheral Artery Disease 1st Edition by Emile R Mohler, Brian Annex – Ebook PDF Instant Download/Delivery: 0128013443, 9780128013441
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Product details:

ISBN 10: 0128013443 
ISBN 13: 9780128013441
Author: Emile R Mohler, Brian Annex

Regenerative Medicine for Peripheral Artery Disease is a comprehensive and up-to-date resource on the use of regenerative medicine for the treatment of peripheral arterial disease. This reference includes a general overview of regenerative medicine and covers important vascular topics, including intermittent claudication and critical limb ischemia, with important mechanisms clearly presented in full color images throughout the book. This important reference includes clear and concise information on both human clinical trials, as well as important and pertinent animal studies, and is a must-have reference for researchers and practitioners of peripheral artery disease.

  • Compiles and explains the rationale and history of different regenerative treatment concepts for peripheral artery disease in one reference
  • Presents pertinent animal studies and human clinical trials in the area of regenerative medicine for peripheral arterial disease, addressing both safety and efficacy of the clinical trials
  • Provides full-color images that demonstrate covered mechanisms
  • Includes access to a full-color website for further study

Regenerative Medicine for Peripheral Artery Disease 1st Table of contents:

Chapter 1: Angiogenesis in Peripheral Artery Disease: Focus on Growth Factor Therapy

  • Abstract

  • Introduction

  • Growth factor therapy in peripheral artery disease

  • Fibroblast growth factor

  • Vascular endothelial growth factor

  • Hepatocyte growth factor

Chapter 2: Regenerative Cell Therapy: Historical Background and Future Directions

  • Abstract

  • Introduction

  • Historical overview

  • Current treatments for PAD

  • Preclinical and clinical trials for PAD

  • Future direction in PAD

  • Conclusions

Chapter 3: Bone Marrow–Derived Cells: From the Laboratory to the Clinic

  • Abstract

  • Isolation and characterization of bone marrow mononuclear cells

  • Preclinical evidence for BMMNC benefits in PAD

  • Potential mechanisms of BMMNC in PAD

  • Clinical trials using BMMNC for CLI patients

  • Clinical trials using subsets of BMMNC for CLI patients

  • Conclusions and future directions

Chapter 4: Mesenchymal Stem Cells for Treatment of Peripheral Vascular Disease

  • Abstract

  • Clinical need

  • Mesenchymal stem cells

  • Mesenchymal stem cells and angiogenesis

  • Comparison of isolated mesenchymal stem cells with other cell populations: preclinical studies

  • Comparison … : clinical studies

  • Clinical trials design considerations

  • Treatment of critical limb ischemia

  • Unselected mesenchymal stem cell populations

  • Comparison … with other cell types

  • Mesenchymal stem cells for intermittent claudication

  • Meta-analysis

  • Isolated mesenchymal stem cells

  • Remaining challenges

  • Conclusions

Chapter 5: Endothelial Progenitor Cells for Vascular Medicine

  • Abstract

  • Endothelial progenitor cell

  • EPC-based therapeutic angiogenesis

Chapter 6: Mature Cell Activation

  • Abstract

  • Disclosures

Chapter 7: Imaging for Regenerative Therapy for PAD

  • Abstract

  • Introduction

  • Magnetic resonance imaging and spectroscopy

  • Contrast-enhanced ultrasound

  • Radionuclide imaging

  • Conclusions

Chapter 8: Endpoint Assessment for Cell Therapy in Patients with Intermittent Claudication and Critical Limb Ischemia

  • Abstract

  • Introduction

  • Endpoints used

  • Review of prior studies

  • Issues with endpoints

  • Analysis of outcomes

  • Group efforts to define endpoints

  • Path forward

  • Conclusions

Chapter 9: Endpoint Assessment for Critical Limb Ischemia for Cellular Therapy

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Tags: Emile R Mohler, Brian Annex, Regenerative Medicine, Peripheral Artery